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  1. Big_Dad

    Talking GLP-1s with Your Doctor

    The GLP-1 class label covers different mechanisms. Semaglutide is a single receptor agonist; tirzepatide adds GIP activity. Same category, different pharmacology and different NDCs. The distinction matters for prescribing.
  2. Big_Dad

    Can I take my shot a little early?

    Taking it a few days late is fine. Weekly dosing has some flexibility.
  3. Big_Dad

    First major milestone!

    Under 220 is a real milestone. The pattern of where it comes from first is completely individual - most people see it shift around eventually.
  4. Big_Dad

    Under 200! Woohoo!

    I'm down 106 lbs since last November! Still got about 60 to go, but feeling great. Sticking with 13.5mg right now. These meds are amazing!
  5. Big_Dad

    Under 200! Woohoo!

    Awesome news!!! Congrats! 🎉🎉🎉
  6. Big_Dad

    GLP-1 gut issues anyone?

    my sleep apnea was borderline — ahi at 14. before weight loss with my cpap on auto it was 1.25. quit the sleep clinic and set it myself after research. running 8–15 pressure and it works way better for me than auto did.
  7. Big_Dad

    GLP-1s and Chocolate?

    I saw something about the FDA possibly restricting compounding pharmacies from making certain peptides. Has anyone else heard about that?
  8. Big_Dad

    Down 100+ lbs, off meds 6 months!

    truly life-changing. lost about 100lbs, way better than i hoped. got me into healthy BMI range. weight finally stabilized so i'm lowering my dose. if rashes develop under belly flap, get them documented. insurance won't pay for skin removal without documented issues not responding to treatment.
  9. Big_Dad

    GLP-1s and Chocolate?

    Lindt is my go-to treat now that I am on MJ!
  10. Big_Dad

    GLP-1s and Chocolate?

    That could be true. I used to avoid chocolate completely because it would trigger a total binge. I'd eat the entire box of whatever it was. Now, I have confidence that I can eat just one piece, enjoy it, and then not think about it. Maybe we are buying chocolate with this new feeling of...
  11. Big_Dad

    GLP-1 maintenance - what's working?

    felt appetite suppression right away on even the lowest dose. lost fat in the first month but might've been boosted by quitting alcohol. just finished my first month and now I'm hungry the last few days before my next shot. thinking about upping the dose but not sure about doubling. you exercise?
  12. Big_Dad

    Tirz woes - 2nd week slump!

    For me it was hitting 200 after starting at 280, then I plateaued for 2 months trying to drop the last 6. Dropped from 15mg Tirz to 12.5 for a week, 10 for a week, stayed at 10 for 3 weeks. Then decided I wanted 100 pounds down, bumped back to 12.5 then 15. Lost another 14 in 5 weeks. Almost...
  13. Big_Dad

    Mounjaro stopped my hot flashes?

    Same here, I'd love that side effect.
  14. Big_Dad

    One year down! Woo!

    I hit my 5 year mark this January and I’m heavier than ever.
  15. Big_Dad

    One year down! Woo!

    Fantastic progress!
  16. Big_Dad

    Down 50+ lbs since spring!

    That's fantastic! You're probably adding years to your life. It's really good work, and a true testament to your commitment.
  17. Big_Dad

    Down 50+ lbs since spring!

    Yes, keep going! Thanks for sharing, you're looking amazing! 😊
  18. Big_Dad

    Down 50+ lbs since spring!

    You're crushing it!
  19. Big_Dad

    Pics: 2 years later, still going!

    Your daughter looks great too! Plus, she looks bigger in the after photo.
  20. Big_Dad

    Pics: 2 years later, still going!

    Outstanding work!
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