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Pre-auth after 65 pounds lost is documentation bureaucracy, not clinical judgment - the step therapy denial is a formulary rule. Involving an endocrinologist or obesity medicine specialist often provides the override pathway a PCP cannot access directly. Holding at 170 while this resolves is...

Group purchases move faster but skip the individual vetting most people do solo.

Skin removal or acceptance - both are the real endpoint of that kind of loss.

Had gallstones from weight loss, stopped meds for a bit. insurance dropped me after. found a vial in my fridge that's been there a year, not cloudy just condensation, within date. should i use it?

I don't think they are exceptional at much. But I do agree with everything else you said, and I'm happy to see someone noticing how companies design study groups to game the system and get approval. At this point, I wouldn't be surprised to see a study where they used a group that had just come...

Sometimes the pharma companies do "lazy" science reporting: FDA Warns One Company for Not Reporting Deaths and strokes. https://www.medpagetoday.com/public...Nordisk for,PADE investigation, the FDA noted

For some perspective, here are some plots from the retatrutide phase 2 data. At the 1mg level you can see that a pretty good portion of people were still pretty close to the 0% line after nearly a year. But I'd bet that with the 12mg group, there wasn't anyone who hadn't lost any real weight...

I get mine through another telehealth platform, its easier instead of doing monthly appts with my PCP.

I'm really hoping that changing my lifestyle while on this med will help me keep the weight off after I stop. I've been lifting weights and hitting the gym pretty hard. Hopefully, that will make a difference.

I’m considering stopping or drastically reducing too. I find it so hard to stay motivated to eat well. I still exercise because that was already a habit, but I'm definitely less enthusiastic about it. I'm miserable overall. Also, I stopped losing weight after the first month, so it feels like...

I've been using an online service, and it's worked out pretty well for me so far.

What dosage were you taking? Maybe a smaller dose would help your body without so many side effects, like the lack of motivation. Also, it takes about a month for the medication to fully leave your system, so the past month of running, gym, and healthy eating was still influenced by the drug...

I love seeing before and afters, especially face gains. It's amazing how much weight we can carry in our faces that we don't even realize! I dropped about 60 lbs addressing T2D, and I look like a totally different person.

Wow!!! Congrats! 🥳👏

Amazing transformation. What was your daily diet like? What did you eat most often, and what was your approximate daily calorie count?

Starting the same thing with Reta, following this thread.

I appreciate all the insights! I'll adjust my protocol and observe the changes. Hopefully, it's just a temporary blip.

Thanks for the input, Taylor37. I'll keep that in mind and experiment with the TESA dosage to see if that's the issue. It's possible the water retention is masking fat loss too.

My lab rat is currently administering 7.5mg of tirz and 4mg of reta. (They also have some NAD+, Mots-c, and KLOW80 cycles going). Last night, they started experimenting with TESA. Their weight loss has stalled this past week, with a slight increase on the scale. While that's not definitive...

Yeah, you really do! Awesome progress! So happy for you!