Wow, great job! I'm also working toward a similar goal! I'm a 65-year-old male, started at 374 lbs, now at 318 lbs, hoping to get down to 225 lbs. Started the meds mid-January '25, currently on 10 mg. Keep up the fantastic work!
What other lifestyle changes did you make along with the medication? I've been on it for about eighteen months with very little progress, only about 20lbs.
Oh yeah, the constipation is a real thing! For me, psyllium husk has helped a lot. Also, make sure you're drinking tons of water. Some people swear by Milk of Magnesia, but I haven't tried that personally.
I've been on Mounjaro (tirzepatide) for about six months now, and it's been a game changer for my diabetes. It's a dual GIP and GLP-1 receptor agonist, which I understand boosts insulin release and reduces glucagon. I've dropped about 30 pounds, and my blood sugar is so much more stable.