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Exendin-4, the first GLP-1 receptor agonist, was isolated from Gila monster venom - that part is real. Modern sema and tirz are fully synthetic peptides with no animal-derived production.

The blood pressure benefit shows up as weight comes off - most people see it improving within the first 20-30 lbs. Good first step starting here.

Ha, same. The candy aisle thing is so specific. I used to loop past the snack section every single time and now I genuinely have to remind myself it is there. The rewiring is real.

first time i lost weight fast and easy, felt amazing. stopped when i got pregnant. started again six months after and it's half as effective. weight loss is slow and the cost makes me wonder if it's worth it anymore.

So, if you stop taking something that suppresses your appetite and then go back to eating how you did before, you gain the weight back? Groundbreaking!

Some addiction psychiatrists are running studies on how these meds can treat chemical addictions in the brain. This might be one of the best pharmacological treatments ever! Praise the pharmaceutical industry!

Well done! I'm proud of you, too!

I stopped and actually dropped another 5 pounds after stopping. I'm sure some days I eat more and some days I eat less, but I eat around 1500 calories minimum. It sounds like you are undereating. I stopped taking it last May. My current weight is 175 lbs (5'8"). I'd suggest spacing out the...

I've heard GLP-1s can reduce addictive behaviors.

Mostly a Zone diet, and about 30 mins of cardio 4x a week. Nothing too crazy, just trying to be consistent.

Used the first, and now on the second med.

My doc suggested Miralax daily. Metamucil can help too, but drink lots of water with it!

Soluble fiber might also be useful. And probiotics such as Florastor Advanced. Diarrhea is what my pharmacist warned me about the most, saying it's a common reason people quit taking tirz completely. For many on GLPs, it can be the worst they've ever experienced, especially if they had IBS-D to...

Some reading material: another forum another forum another forum another forum

It's truly remarkable how weight loss can bring out one's natural features. In the 'after' photo, your eyes seem to sparkle even more. Congratulations on your journey!

Incredible work! Well done!

Let's give a huge round of applause! 👏

That's fantastic! I commend you. What sparked your initial drive and how long did you manage to stay focused? I'm struggling to stay motivated. Also, what kinds of exercise did you do? Cardio, strength training? And how often?

Incredible transformation! You're doing fantastic. Here's to a healthier and happier you. Absolutely stunning!

Two years ago I asked my doc for help with weight and pre-diabetes and he started me on weight loss meds. Best health decision I ever made.