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Been on HRT for over two years and nothing moved till I added tirzepatide. Lifting twice a week, 3-4 mile walks, counting calories and macros—nothing worked. HRT fixed the sleep and hot flashes but not weight. Tirz solved it. Any woman who can do HRT should look at GLP-1 too.

confused about tesamorelin dosing. clinical trials used 2mg daily but the fda-approved version is 1.4mg. why the gap? other gh secretagogues don't always work better at higher doses either. anyone know why fda went lower?

I've heard of people doing microdoses to manage side effects when they first start, or even titrating down. It might be worth exploring if you're concerned about jumping back to a higher dose too quickly.

To Sema-Siren's question about batch reconning, freezing, and filtering later: I wouldn't recommend it. It's just adding an extra step where something could go wrong. Better to filter fresh.

Also, if you're experiencing any skin reactions like hives or rashes, it's crucial to monitor those closely and report them to your doctor promptly. Allergic reactions can sometimes occur with these types of medications.

I try to keep my fiber intake consistent with chia pudding, oats, veggies, fruits like prunes and pears, and whole-grain bread. I use Meagain to track my food and see if there are any culprits and if I'm getting enough fiber. Other things that help me: * Water (not just coffee) * Short walks...

If it's been in the fridge the whole time, you should be okay. The expiry dates are usually cautious. The bigger problem is the dosing mix-up. Don't take another shot to compensate – just stick to your normal schedule next week. Being a little under-dosed for a week is better than side effects...

It's not only about water or eating well, it's often about electrolytes. You could drink 64oz of water but still need electrolytes. I was getting awful headaches even when I was drinking tons of water. I started using electrolyte powder, and the headaches stopped. The directions say to use 16oz...

I've had some luck with Mag 07.

First thing: toss those expired pens if they worry you. But honestly, you did this backwards! Always use the older pens first. If you're moving from 7.5mg to 10mg, finish the 7.5mg pens before starting the 10mg.

I don't remove the filter from the needle once it's in the vial/cartridge. I assume any needle that's been taken out is contaminated. So yep, single-use only. I prime the filter with a separate syringe before filtering. For a starting dose of 2.5mg, I'd mix to 1mg per 10 units, or 2mg per 10...

Also, what if you happen to find an older pen in the fridge from a previous dosage? Is it okay to use an expired pen?

Confirming: 36 clicks for a 0.5 dose. Want .75? That's 54 clicks on the pen.

Funny, I was just talking about this with my Botox injector. I'm one of those folks who are always close to goal, yoyo-ing, with an extra 15 lbs. I eat a mostly clean diet, but I always gain it back after sema; never more than I started with, though. I'm losing with Reta now and she recommended...

Every time I even THINK about lacing up skates or grabbing a skateboard, I can see the hospital bills flashing in my wife's eyes. 😢

You can do both, Riley2008: tell them it works well, and also tell them the risks of stopping, no matter how much they want to lose.

Since the data is so clear on weight regain, people should just plan to stay on them indefinitely. It's like trying to use some other experimental drug to maintain the loss – doesn't seem smart. People don't expect to stop taking statins once their cholesterol improves, so why the fuss about GLP-1s?

How much further to your target? Always curious what folks are aiming for height-wise.

It's truly remarkable what these medications can achieve. I've seen individuals shed over 100 pounds with similar treatments. The advancements in diabetes and weight management are astounding.

I think you look fantastic however you choose to present yourself. My sympathies to you and your family regarding your mother.