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3 weeks of thinking sema wasn't working because of RNY and small portions is such a common misread. The RNY changes absorption timing enough that the effect often comes in a different pattern than typical users. How far into it now and how is it comparing to the first 3 weeks?

5 months at 2.5mg with zero appetite and still struggling to eat is actually a useful data signal for when to stay put rather than push up. If the mechanism is already fully engaged at 2.5mg, going higher often just adds side effects rather than benefit. The question for long-term management is...

50 lbs in 6 months for both of you and then forced to stop due to cost and availability with the regain aftermath is the cautionary version of what the OP is managing on the way down. Going back down on dose and feeling like things are slowing is often the body defending a new set point rather...

The receptor sensitivity myth about once-weekly dosing has been effectively disproven by the pharmacokinetics - the relevant half-life and receptor binding kinetics don't support it. Dosing every 5-6 days based on where you feel the end-of-cycle hunger returning is a rational adaptation...

The local injection debate for injury-targeted peptides is genuinely unresolved in the evidence - BPC-157 and TB-500 are systemically acting compounds rather than purely local ones, which suggests the injection site may matter less than generally assumed. The case for proximal injection is that...

That's incredible progress! Started on Ozempic and barely moved the scale - only 6lbs in 6 months. Switched to a compound and Mounjaro and saw 22lbs in another 18 weeks. Now trying Berberine on the side to get the last 7. Wild how different each option hits.

To help you out, I also have PCOS, and it's helped my cycle become more regular. I used to go for months either bleeding or not bleeding. I also use ground flaxseed, and that's helped me too.

62 and wasted 24 weeks on Ozempic—only lost 6 pounds. Switched to a compounded version and then Mounjaro. 18 weeks, 22 pounds lost. Now on berberine for the last few pounds and maintenance. Got a cousin who gets horrible nausea the day after her shot but she's losing steady.

Got on GLP1 partly to treat my drinking. Did Naltrexone, Campral, but GLP1s worked best. First time drinking after starting I almost always threw up after a couple shots. Life-changing and hoping it gets FDA blessing for addiction soon.

gyc selling black top r15 with a heads-up that it might recon cloudy but you can fix it with pbs. warning if you can't handle that. checked their site & it's gone so they had buyers. eu warehouse is $140.

Had bad gag reflex issues after starting—way more sensitive now. It's never been enough to quit but def had to be careful at work. 13 months in and finally weaning off after hitting my goal.

the fatigue hit me too and it's still here. you're not a bad mom for struggling — your body's carrying a lot while you're trying to take care of yourself. losing weight is actually gaining health for your whole family, even if this stretch feels heavy.

I switched to another tracker recently that is totally free with almost the same stuff plus extras. Started as just a site and now has an app that is way easier. Team is real responsive, say more features coming, so probably a paywall eventually.

Same here. Went from 210 to 115 in 13 months—an inch taller and bit older than you. But I was undereating, overexercising, spiraling on health anxiety and obsessing over every number. Stop wearing the health tracker. Let doctors handle it. See a therapist about the obsession.

Only place I saw that was one vendor or they go to messages. Most respect their terms. One even swapped a whole batch after testing showed weak. Older vendors tend more reliable. But there's been...

Dang, looking incredible! The glow up is real. (Writing this as pure observation from someone happily married lol)

Studies show the worst GI stuff usually happens months 2-4 when you're titrating up. Lots of variation tho. Might ease up in a few months. PPI's short-term might help if there's stomach irritation, especially with reflux which is super common on these meds.

my stomach was surgically shrunk to walnut size in 2003. back then i measured meals with a cough syrup cup. but here's the thing—the body adapts. 23 years later i can eat half a pizza. reducing stomach size doesn't guarantee long-term weight loss.

been off almost two years. some days food noise is loud but trained myself better habits now. stomach smaller, fill up faster. eat slower helps. kept weight off even lost a few past my 135 goal, at 125 now. started almost 200.

started at 282, down to 240, goal is 200 and target is 185-190. i'm 6'1-2 so 190 puts me in normal bmi range. i was 225 in college doing rotc pt then lost the muscle over 20 years. target is where i'd finally see abs based on my projected body fat.