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I stopped completely at 8mg and switched to Tirz at 5mg. Many advise lowering the dose before stopping but I was finished, it wasn't doing what I needed. On Tirz the food noise vanished within the first hour, and I even got that old fullness without eating, which I'd missed on Reta. My water...

Not much science exists on cycling GLP-1s, so we're mostly relying on anecdotes. Judging by numerous posts I've seen, restarting after a break often isn't as good, and higher doses seem to be needed for results, at least during active weight loss rather than maintenance. I'd guess breaks during...

What worked for me came when my target weight arrived in late January, 280 down to 200. I stalled for the last 60 days and the final 6 lbs took forever. I stepped Tirz down from 15mg: one week at 12.5, then a 10mg stretch of 3 weeks, planning on maintenance (whatever that means) with my weight...

Some people do no activity at all and still lose weight. Everyone responds differently to both surgery and meds, so you'll need to see which works best. I've heard of people post surgery on glp-1s who are 5 years in and haven't reached their goals. Personally I'm 61 3/4 with no patience, and...

It surprised me that the dietitian I saw discouraged them and had no GLP-1 diet tips, so I didn't book more sessions. Ulcerative colitis is part of my picture and my stool is more formed now. Running hurts less afterward too, letting me run more, partly from weighing less, though it's just 5 lbs...

For me it's been the opposite! I had awful munchies, raiding the kitchen for endless ice cream, chocolate, fruit and snacks; after I began Oz I'm content stopping after a little and the crazy urge is gone. For context, PCOS plus insulin resistance is my background, which might play a role.

Had that exact 'is this even doing anything???' feeling with my first 0.5 shot too! 1mg's been a bit rougher, and my appetite shifted gradually over time. Try not to stress about it! (Easier said than done, I know.)

Heads up, generic just dropped in Canada and Ozempic's price-matching it now. Best deal's at Costco, running $88 CAD for either option. Just got mine filled yesterday actually. Local pharmacy quoted $103 CAD, they charge a steeper dispensing fee.

Wow, you're looking amazing, huge congrats on how much MJ plus the effort you've put in has paid off. Posts like this are genuinely inspiring, especially only 14 weeks into my own journey with roughly 100 pounds still ahead of me. Thanks for sharing, it's great seeing the real difference this...

Went a full 6 months without dropping anything. Was on 7.5 that whole stretch, not losing, not gaining. Then out of nowhere the weight started coming off again. Started at 260, sitting at 168 this morning. Planning 8 more pounds then stopping to just run Mounjaro for maintenance from there. Hang...

Sure thing! Went from 83 kilos back in January down to 59 now. Happy with where things stand and just planning to hold steady on maintenance going forward. First month alone accounted for a 9 kilo drop.

Might've already checked this, but worth confirming the medication isn't nearing its expiration. Effectiveness drops as it ages. Believe it holds up for roughly three months once opened. Shorter shelf life if it's not kept refrigerated consistently.

Same here. Snapped a few side profile shots of my stomach back in October. Now there's genuinely no comparison since it's nearly flat. Sixty-two, female. Helps that I started doing planks once or twice daily starting three months back. Even built a dedicated playlist for it.

Tracking macros and total calories has genuinely been the most useful approach for hitting fitness and weight goals. Keeps intake from going too high or too low, and helps steer choices toward foods delivering enough protein and fiber.

The food noise shifting from 'when can I eat next' to 'did I get enough protein today' is a meaningful change in the underlying pattern - one is about craving and one is about optimization. The OP describing the quiet as a big shift is the first version disappearing. The second type tends to...

Mounjaro killed the food noise almost immediately, like day two. Genuinely been incredible. Seven months in now, down 42 lbs. Also helped calm inflammation, dealing with rheumatoid arthritis on top of ulcerative colitis plus a rare autoimmune condition affecting my liver. Latest labs came back...

The GHK-Cu collagen and elastin production evidence is the strongest of its claimed mechanisms and the angiogenesis pathway is the one that makes post-surgical recovery the most compelling application - improved blood flow to healing tissue is exactly the requirement after any procedure that...

0.25 as the starter dose designed specifically to be tolerable is worth knowing going in. The 'kinda off not knocked out' description is accurate for the vast majority of people at that level. Week 2 is usually where you start to get a clearer signal on how your individual response is shaping...

Regular measurements are the single biggest tool and that's exactly right at the stage the OP is in. 340 to 250 and a size 28 to 20 is visible change but the measurements track the body composition shift that clothes don't capture perfectly at the transition sizes. What's been the most...

the transition-specific cardiac adjustment when switching from one GLP-1 compound to another is worth giving 2-3 weeks before drawing conclusions - the glucagon receptor addition with Reta shifts the autonomic balance in a way that can produce transient palpitations that the previous compound...