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I've lost 60 pounds across several years. I mainly take Mounjaro for T2D, weight loss is the bonus. There were multiple plateaus lasting months and then suddenly 10 pounds gone with no change! Don't get discouraged, muscle gain could be happening, and that's good. You also don't want to lose so...

Test counts as steroids. And no, I wouldn't say everyone has low T, but plenty of folks call things TRT that aren't. I take Reta, 4mg a week, alongside 2iu of growth hormone a day and 200mg of test. Eight pounds are gone in the past month and I added some lean mass. My T really was low...

I'm a 69 year old woman with type 2 plus assorted other conditions, on Mounjaro since 3/24, and I totally agree with you. 27 years of diabetes now, and I tried many diabetic meds, but Mounjaro turned out to be my match. My A1C improved most on it, I halved some meds and stopped others. I...

Appreciate that, interesting seeing how everyone else approaches this. I ramped up on Reta pretty fast myself. Hit 4 total for reta by week two (running 2mg twice that week). Then did 3 and 3 this week. No issues so far. Only real change is the food chatter feels louder overall while I'm just on...

No way for me personally, alcohol and fried food hit like a truck, genuinely scary. Greasy stuff leaves me nauseous but bearable, ice cream's totally fine though. Everyone's different, but honestly I'm perfectly content giving up drinking.

You need one more container to round out that set. Kind of jealous honestly. I just label each vial and toss them back in their original box, then stack those boxes inside a bin that lives in the freezer, not nearly as tidy as what you've got going.

Ever tried mixing baking soda into water? Wiped out my burning throat and heartburn completely years back.

Remember you having to pause around a surgical procedure. Even a brief break from these medications genuinely scares me. Keep climbing that dose, friend!

Oh honey, this reeks of a scam. Payment app requests? Shirtless profile photo? Random unsolicited messages? Definitely risky territory. Stay careful!

Don't tell a soul honestly. My oldest kid knows we're running reta, since he's actually the one who got us into it. When friends ask how we dropped so much weight, just say low carb eating. Two pounds a week holds up fine as an explanation if anyone pushes.

the 1mg-to-6mg arc is useful context for calibrating what to expect at each step - most people find the early increases come with more noticeable appetite changes than the higher-dose increases, where the marginal benefit per mg starts to taper. knowing where in the progression you actually are...

If 8mg is where you should have felt it and didn't, that's useful information. Adding Tirz back in alongside is one path and the nausea at 6mg Tirz is worth understanding first - is that from the Tirz dose itself or from something else in the protocol?

the mitochondrial health dependency for MOTS-c is the piece that explains a lot of the no-effect reports - the compound works through the AMPK signaling pathway, but that pathway requires baseline mitochondrial function to produce any downstream benefit. people with existing mitochondrial...

Setting the second goal weight before even celebrating the first hit is the sustained momentum approach. 262 to 162 is already a C-note and you're still going. Keeping the same routine that got you there rather than changing anything is exactly the right call.

The metformin foundation mattering more than people realize is a fair point - the metabolic prep that happens in that phase often sets up a better response when GLP-1 comes in. The OP at 80+ lbs and still going from a 330 starting point is the long game in progress. Still on track is a great...

Second round is actually a common story - Wegovy working for a while, stopping, gaining back, and then coming in with Zepbound. The cravings-worse experience the OP has on Wegovy at 2.5mg is unusual enough that switching mechanisms makes sense rather than pushing the Wegovy dose higher. How has...

Starting GLP-1s after losing most of the weight yourself and finding them mainly useful for keeping it off is a different use case than most people here. 145kg to 75kg on your own first and then using it for maintenance - that's an interesting model. What made you decide to add it at that point...

18 lbs in two months split dosing Monday and Friday with no plans to push dosage higher because it's already working is exactly the right mindset. 2 lbs from goal at 2mg/week is a clean result. The 283 to 258 in the OP is right in line with what consistent split dosing looks like.

2mg to 3mg after a couple more weeks is a sensible pace to get a clean read at each level. The OP adding GLOW to the mix at 3 weeks on Reta is an interesting log to follow. How much of the 9 lbs do you think was water in the first week versus actual fat loss trending?

the draw-needle-then-swap approach is worth the extra step if you're drawing from a rubber-stoppered vial - the stopper dulls the needle tip enough that you can feel the difference, and a fresh tip for the actual injection reduces both pain and the micro-damage at the injection site. luer lock...