Down 80+ lbs - Still Going!

Hong Kong Yanpep International
Been in those shoes! I started mounjaro back in December, traveled in March, down about 60 lbs by then. Still a big guy for sure, but I could finally tell folks I wasn't the biggest I could have been. Haha!
 
Depends on what you're after and who you ask, honestly. Most of that stuff is still being studied. General advice is SS31 first, then Mots-C for better results, but timing matters too.
 
2.5 years in and it still works. Turned out it helps my autoimmune stuff and the old nerve damage too, so I'm staying on it til my country approves it for these other conditions. Then I'll switch to a prescription and keep going.
 
The fibre-first approach is the right call for GLP-1 constipation - the slowed gastric transit makes the stacking effect of bran, beans, and kiwi more effective than any single source. 80 lbs down from 330 at a steady pace is what the full protocol looks like when the basics are handled.
 
Didn't expect much from the weekly shot but it worked strong the first few days, then wore off around day 4 or 5. Just listened to my body about eating. Three weeks in and I've lost 23 pounds. I know some of that's water and inflammation from starting at a high weight, but 23 lbs in 3 weeks feels like a lot. Anyone else experience this?
 
The social eating reframe is the underrated part - presence at dinners without the eating pressure changes the whole dynamic. 80 lbs off plus dropping two medications is the compounded outcome.
 
330 to 248 with no exercise capacity due to knee and shoulder issues is a strong result that challenges the idea that the medication only works alongside movement. The joint load reduction as weight comes off often opens up activity that wasn't possible at start weight - many people find they can add walking or resistance work around the 60-80 lb mark when the knee stress drops enough.
 
The Metformin add-on at plateau is a well-supported combination - it works through a different mechanism than GLP-1 and the two together produce more sustained results than either alone for people managing T2D alongside weight loss. Your doctor is using the evidence-based playbook.
 
18 lbs with appetite under control at 0.5mg is a perfectly calibrated start. the ED brain framing of 'going slow' when the actual data says progress is happening is something a lot of people recognize here. always ran cold and now running hot is such a specific physical tell of what the weight was actually doing. so much progress from 330.
 
Nearly 30 lbs since December at 10mg plus metformin is the combination that tends to work better than either alone for T2D patients. The OP at 330 down to whatever the current number is on multiple diabetes meds is the version where the weight and blood sugar picture are moving simultaneously. The range where things slow down is usually around 20-25% total bodyweight lost - how are you tracking it?
 
15 kg in 9 months feeling disheartening compared to the OP's result is the comparison problem these posts create. 15 kg is real loss and 9 months is not a long timeline at all. The OP at 330 had a very different starting point which drives a very different rate. What dose are you currently on and have you moved up since starting?
 
The metformin foundation mattering more than people realize is a fair point - the metabolic prep that happens in that phase often sets up a better response when GLP-1 comes in. The OP at 80+ lbs and still going from a 330 starting point is the long game in progress. Still on track is a great place to be.
 
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