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Never had a dose hold beyond four to eight weeks before needing another bump. On 1.7 currently and hungry pretty often, but I can talk myself out of eating or just wait it out. Personally haven't noticed side effects getting worse with each increase, for what it's worth. Lots of people hesitate...

Really solid insight here. Definitely feeling fuller after meals. It's clearly doing something at 6mg. Not scared to push the dose higher, just want to give this level a solid four weeks first before deciding. Running one of these medications indefinitely genuinely doesn't worry me. If it keeps...

Yeah, landed on the same conclusion myself. Taking it slow with a second vial that I mixed and ran through a filter this time. Holding steady so far. Honestly no idea what the actual root cause was, my working theory was some kind of sterility issue since filtering seemed to fix it, though it...

I hit a 3 to 4 month stall at the exact same weight roughly every 5 months. Pretty sure it's because I'm just not eating enough during those stretches, body figures it's in starvation mode and clings to the weight instead. Genuinely struggle to eat enough on tirz though. Still trying to figure...

When my spouse first started on the GLP, insurance covered it fully, just twenty five bucks monthly for the injections. She was prediabetic, right at the edge of full diabetes. Then the policy changed and coverage got pulled since her bloodwork didn't technically confirm full type two status...

Congratulations! Mounjaro genuinely saved my life too. Down over 75 pounds in a year and a half, my doctor says menopause is probably why it's not even more. Went from a size 22 down to 12, almost fitting into a 10! Both conditions, diabetes and heart failure, have gone into remission. Walking...

Shipping samples to a testing lab runs somewhere between ten and fifty dollars. The actual tests themselves cost a few hundred. And a full vial of that lyophilized compound from a kit runs maybe ten to twenty dollars.

Starting to think maybe I need more caffeine in my life... any research linking coffee intake with GLP1 medications or other peptides? Edit: could just ask directly what the deal is with coffee and see what people say, ha.

That sweater comparison is wild honestly. The fit alone tells the real story here, way more than whatever the scale says. Huge congrats on sticking with this for nine months straight.

Yeah, this matches what plenty of others have said. It's not purely appetite related, from what I understand this class of medication acts on brain receptors directly, not just in the gut. Newer research points to those receptors showing up in spots connected to mood and stress response, which...

Those cap colors are so nice! Curious if those are all the same size or a mix of two different ones? The set on the right almost looks bigger, though that might just be how the photo's angled.

Only ever mixed reta and aod with bac water myself, always came out perfectly clear. Not sure what would explain them telling you otherwise.

Appreciate it. Prefer needle attachments similar to one particular pen style. Wasn't a fan of the single fixed injection style from the other. Barely registered anything from the needle whatsoever.

Feels like the very last pockets of fat get stubborn about disappearing. After dropping 80 kilos and landing around a body mass index in the low twenties, I still carry a fair bit of subcutaneous fat around my midsection compared to other areas. Only real fix is more fat loss or building muscle...

Pin 4mg reta Sunday, 1mg sema Wednesday, 4mg tirz Friday. Reta broke my stall, might nudge it up slightly, sema kills food noise, tirz helps inflammation. Been on glp meds over four years, maxed sema more than two years back. Switched to tirz but food noise never fully went away, so added sema...

The gastro virus coinciding with the first Ozempic week is a genuinely important data point for the thread - it changes the interpretation of every early side effect report that came before the edit. For the OP feeling terrible, this is worth keeping in mind: the first week of Ozempic can be...

Thanks for that, the writeup was genuinely useful. I'm sitting on roughly 15 of the gray-topped vials at this point. The more I dig into it, the more negative stories I find, but I think that's mostly because people only post when things go wrong. Not much incentive to write in when everything's...

The RHR increase combined with apixaban use is the specific combination worth flagging explicitly to your prescribing physician - apixaban dosing is sensitive to changes in cardiac function, and the interaction picture at Reta doses is a clinical question your doctor should weigh in on.

The diabetes supply channel is the practical cost solution once you're consuming needles in meaningful volume - the same products that pharmacies stock for insulin users at premium single-pack pricing are available at significantly lower per-unit cost through diabetic supply distributors. The...

The difference between not thinking about food at all versus having to fight food thoughts is significant - Reta's glucagon mechanism seems to produce a more complete quieting of the food-thought loop for some people than a pure GLP-1 approach does. The comparison you're describing is exactly...