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Acne flares on Reta in the first couple of months often track with the hormonal shift from rapid fat loss rather than the medication directly.

Sugar alcohols ferment fast in the gut and the GI slowdown on GLP-1s extends the exposure window, which is why the effect tends to be worse than it was before starting.

10 lbs in the first month on Rybelsus is a solid start - oral sema has lower bioavailability than injectable, so that pace is actually good. Dry mouth peaks around months 2-3 and resolves; biotene and gum work until it does. One cheat day doesn't move the arc.

Onederland! Nice work!

Why'd you block part of the pic out? I bet I could still ID you...

That is true. But I'm just not sure the side effects are worth it *for me*. Maybe I'll revisit this later, but for now I'm out.

Update: I stopped the injections. I'm done. Lost 20 lbs, but I feel terrible: sick, nauseous, and constipated. It's not worth the awful feeling, in my opinion. I'll stick to cutting carbs and eating healthy to maintain. Plus, saving $150 a month!

Just started semaglutide injections 5 days ago, and this is my first week. Yesterday I was hit with major hunger. I devoured two helpings of pasta! This morning I felt fine. Any idea why I'm getting these hunger pangs?

That's an interesting thought! I've definitely felt like my food noise has decreased, which helps me concentrate a little better.

I'm feeling a bit more anxious. Maybe I was just good at hiding it before.

Kind eyes!🌸🏵️ Congrats 🏵️🌸

You seem like a very nice person.

It's been about 6 weeks since I switched from 10mg Tirz to titrating up on Reta. My weight loss kinda stalled during the switch, but it's picking up again. The appetite changes are a mixed bag. I kinda miss the feeling of rarely being hungry with Tirz, and being able to eat a small breakfast...

After about 9 months on GLP-1s, my weight loss stalled at 5mg of tirz. Instead of upping the dose, I started adding Reta, starting at 2.5mg. I switched my tirz injections to every 5 days and did Reta on its own 5-day rotation, separately. I read it's better to space them out since they affect...

You really do look amazing! Just like the fairy tale princesses I used to dream about when I was little!

Welcome to our little corner of the internet! Just a friendly reminder: let's keep the discussion focused on approved meds and avoid any talk about buying or selling. If anyone slips into your DMs with offers, please ignore and report. We want to keep this a safe space!

I'm on the generic and taking .25mg. Tomorrow is my fifth dose. I don't think I need to increase yet, I'm down 8 pounds in the first month! Binge eating and overeating are gone, and no side effects. I think I'll stay at .25 for another month and see what happens.

Anyone tried peptide sciences? I saw they were mentioned on another forum

What a wonderful and happy post! I am reading this outside, and the sun feels so good. It made my day! ❤️

Same here! I trust my usual place, but haven't ordered anything at all yet.