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  1. ProteinWine

    Mounjaro for T2D but weight loss stalled?

    The glasses analogy is the right frame - corrective intervention for a metabolic condition doesn't have a natural exit if the underlying condition persists. For T2D specifically, the A1c and insulin resistance data makes the case for long-term use independently of the weight loss benefit. The...
  2. ProteinWine

    Mounjaro pen clicks - how many?

    Disassembling an empty pen is the right way to understand the click mechanism - seeing how the dial works makes clear why audible clicks are the more reliable measurement than counting dash marks on the face, which have wider variation between individual pens.
  3. ProteinWine

    My real weight loss experience with GLP-1s

    TDEE calculator estimates have a wide error margin - usually plus or minus a few hundred calories per day. Using them as a starting point is fine but treating the output as precise is where people get into trouble. The calculator gets you in the ballpark, and then you adjust based on actual...
  4. ProteinWine

    Sema second round -- stalled?

    It's important to remember that these medications are tools to help you build healthier habits. If you go back to your old habits after stopping, the weight will likely return. Focus on sustainable lifestyle changes while you're on the medication.
  5. ProteinWine

    GLP-1 Success Story - My Journey!

    I hear you! Childbirth really does a number on our bodies. I've been researching tummy tucks and 360 lipo for a while now. It seems like a good option to get rid of the stubborn fat and loose skin.
  6. ProteinWine

    Sema second round -- stalled?

    I think you'll see results again, just be patient. Also, rapid weight loss isn't always sustainable anyway. And remember, this is often considered a long-term medication. These meds are meant for managing weight, not just losing a few pounds for a special event.
  7. ProteinWine

    GLP-1 Success Story - My Journey!

    Incredible congrats
  8. ProteinWine

    GLP-1 Success Story - My Journey!

    Finally! I see someone else with the same separation in their belly button area as me! Is that why you're getting the tummy tuck? Was there muscle separation that happened?
  9. ProteinWine

    5A1MQ experiences?

    Update since upping the dose: I increased the RS dose to a little over 7.5mg yesterday and today. (More like 8.5mg each time, since that's all I had left in the vial). RS only slept 6 hours the night before and felt tired before injecting. RS injected NAD, then 20 minutes later, injected 5am...
  10. ProteinWine

    5A1MQ experiences?

    RS means 'research subject' ;) I'm in the exact same boat. Also using 50mg of NAD. RS definitely feels the NAD energy on NAD days. I'm still trying to figure out what the effects of 5am actually are. Hopefully, 10mg will show more promise. I also need to get my RS to sleep earlier. I'm excited...
  11. ProteinWine

    5A1MQ experiences?

    I started researching with 5mg injected daily for the first week, along with 50mg NAD (three times a week). Days 1-2: My research subject had more energy. RS was a beast at the gym. RS also slept well, especially after the first dose of NAD. Days 3-7: Workouts were good. No real change in RS's...
  12. ProteinWine

    Reta Schedule - too much hunger?

    Also Curious_Lemon_45 traveling in Japan means tons of walking! And their food is generally healthier than ours. You'll prob come back lighter!
  13. ProteinWine

    Reta Schedule - too much hunger?

    Hey Curious_Lemon_45, since GLP-1s have a long half-life (about six days), you'll have some coverage for the first week. It will be 1/2 as potent the first week and then 1/4 as potent the second week. If you miss more than two weeks, providers usually tell you to lower your dose when you...
  14. ProteinWine

    Tirz at max dose + cagri?

    Interesting about SLU-PP-332 - never heard of it. I'll have to research it. However, I'm a bit skeptical about replacing clen and DNP. Those are seriously heavy hitters, and the risks are well-documented. If something sounds too good to be true....
  15. ProteinWine

    Tirz at max dose + cagri?

    When you're at the highest dose, yes, you surely can do that. I mix it with reta at just 0.25 mg, and it works great with no negative side effects.
  16. ProteinWine

    Tirz at max dose + cagri?

    Definitely. Since you're at the highest dosage on tirz needing an extra push, you could consider this. Start with a low dose, like 0.125mg. I combine reta and cagri. Cagri has been great for me, with zero side effects. It's worth knowing that some may experience severe fatigue or nausea.
  17. ProteinWine

    Half my size! Woohoo!

    Incredible progress! I'm also 5'6" and started sema about 5 months ago with a starting weight of 223. My loss is slower. What dose are you at now, OP?
  18. ProteinWine

    Under 300 lbs again! 🎉

    Huge congratulations to you!!! So proud of you! I’m on Mounjaro 12.5, and it’s been really slow. Are you adding in more exercise and eating less? I’m still trying to get those two things under control. I LOVE hearing about your success and everyone’s success. It's basically a miracle powered by...
  19. ProteinWine

    Under 300 lbs again! 🎉

    Fantastic! Congrats!
  20. ProteinWine

    Half my size! Woohoo!

    That's absolutely fantastic! You've clearly put in so much effort, and it's paying off!
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