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MOTS-C for fat loss stacks well with cardio - the mitochondrial activation is most pronounced when combined with aerobic exercise.

Size 20 to size 14 is more than a number - that's the kind of visible shift that changes how you carry yourself.

Thrifting through the drop is the right call - you cycle through sizes too fast to justify buying new. The underwear exception is the one category where fit actually matters in real time.

Look into intermittent fasting. Read "The Obesity Code" by Dr. Jason Fung.

Whenever I see posts like this that don't mention calorie tracking, I wonder if you have all the information. That might be the answer to the regain.

So, if you stop taking it, does all the weight come back?

I used to wake up feeling stiff and achy, but that's gone now. Obesity can cause fatty liver, which then causes inflammation.

I'm new to all of this. What exactly is retatrutide? Is it like Wegovy?

Inflammation makes you retain water. When it decreases, you drop the extra fluid and look less puffy. I think that's one of the first things that happens on these meds...you might not see a huge weight change right away, but your face and hands look different. I didn't realize how inflamed I was...

Mine has vanished entirely. I used to enjoy it a lot. Not missing it that much though.

Thanks everyone for the support! Flex_Tale, I honestly haven't noticed a huge difference with the fibromyalgia, but it's hard to tell with all the other things I'm on. Good luck to you all!

Actually, it's been the opposite for me since starting Zepbound a few months ago.

Okay everyone, here's my update! I'm 48, female. Started at 323 pounds; now I'm at 269! So, down 54 pounds! I also deal with: Hashimoto's Thyroiditis (with meds) Anxiety/Depression (also medicated) Fibromyalgia ADHD ARFID (Avoidant/Restrictive Food Intake Disorder) I'm in the UK, and my...

I had crazy constipation at first. What has been working for me is eating about 6 prunes every morning, a spoonful of Metamucil with sugar free Gatorade, a spoon of chia seeds in yogurt, and fiber gummies. I also drink at least 60oz of water. Good luck!

Did they test to see if you have gallstones? I had an attack after I lost 60 lbs in 5 months. It happened after eating foods with higher fat.

Yeah, BrookDaily I had that problem once. I switched needle brands and it seemed to fix it.

Fingers crossed she listens! Keep us updated! ❤️

I just told my doctor that I get my compound meds from an online pharmacy. We already talked about how the branded drugs were too expensive, so she knew I would go that route. I just didn't say that *I* was the compounding pharmacist. LOL

That sounds like possible congestive heart failure or kidney problems. She needs to see a doctor, ASAP. I'm not a doctor, and this isn't medical advice, but seriously, get her seen.

I saw a post about someone who lost 55lbs since starting Ozempic in October 2022 and is now pausing... seems scary! Good A1C and off metformin though! Congrats to them