Search results

Glycine as a GLP-1 adjunct is an interesting angle. It's a common co-formulation in compounded tirz partly for osmolarity reasons but also because glycine has its own mild metabolic effects - GI motility support, collagen synthesis, some GABA-adjacent sleep/anxiety effects. The interaction with...

GLP-1 has documented anti-inflammatory effects beyond weight loss. Joint symptoms improving out of proportion to the scale changes is a consistent pattern here.

Stomach bugs on top of sema are rough because delayed gastric emptying means everything hits harder and lasts longer. Protocol when actually sick: pause or delay the dose if nausea and vomiting are already bad, focus on hydration above everything else, and hold at the current dose rather than...

here's the thing — if you're diabetic and stop, the weight almost always comes back. i lost a ton in the first few months, about 31 kilos, then plateaued hard. but my A1c tanked from 7 to 5.1 and stayed there. feeling better than i have in years.

Been on Mounjaro 20 months, down 70 lbs, about 23% from peak. Started 2.5mg, now 7.5mg. Hit two plateaus. What helped: dose increase (last resort), changing injection site — thigh's best for me — and moving shot day to when you're busiest at work so less fridge access and less food temptation.

started at 2.5 and added 2.5mg every 4 weeks. just hit 10mg. losing 1.6-2lbs a week steady, no plateaus so far.

Went to 7.5 after a long stall and it's been rough—nausea, insomnia, dizzy spells. But I finally broke through. New insurance won't cover it anyway so one shot left. If you're still losing at 5, stay there till you stall a month.

Exactly! I lost about 25 pounds on my own through diet and light exercise changes. Then starting Tirzepatide just made everything easier – and it was like the weight came off without a struggle. It really amplified what I was already doing!

This is honestly the only subreddit where I get downvoted regularly for simply sharing my personal stories, not even offering advice or opinions.

It's wise to be cautious. I worry a bit about topical finasteride absorption, even though it's supposed to be localized. I'm not sure how I feel about the reports of ED and depression even with topical application. Proceed with caution.

I found this community a couple of years ago and spent weeks soaking up all the information about Tirzepatide and how it was improving lives. Without this group, I never would have started. It wasn't just about the weight loss stories; it was the stories about overcoming addiction that really...

That's so sweet and supportive!

That's a great trend to follow. The first bit comes off fast, then it takes twice as long for the next bit, then even longer for the next. But it still leads to a gradual reduction. That's been true for me too. Congrats!

That's amazing, Chris02! Congratulations on your progress!

I'm glad to hear I'm not the only one losing weight. Just hit a new low since a few years ago! It's like a new life. I'm a woman over 40, so I'm amazed I can shed pounds this fast!

I use the V1 because it has a cap. The V2 is open. Sometimes they're hard to push, but I figure it's the cartridge stoppers. I want to control the injection rate. I like the colors too, easy to tell them apart. I haven't tested their accuracy.

fascinating...They will be sucked out while still inside a pouch?

How did you loosen the stoppers if they were inside the cartridge?

Yeah, my last batch was like water. Did you get the clear liquid? It used to be milky.

I have as much faith in a test report from one lab as I do from a peptide vendor - zero. Based on tests of the same batch from multiple labs, that lab is a weirdo.