I get noticeably wiped out the day or two following my injection, which is why I do it Friday nights. Definitely plan to sleep in more during those days. Also deal with mild nausea, nothing severe though.
Honestly hard to judge whether it's worthwhile without pairing it with real effort of your own. Picture watching your meals more closely and actually seeing results on the scale, would the tradeoffs feel justified then? If the answer's yes, commit to that for thirty days and reassess afterward. If the reactions still feel unmanageable regardless, this particular medication might not be a fit for your body.
For me personally, the side effects have absolutely been worth the 40 pounds gone since starting in February. Only just moved to the next dose tier a couple weeks back, so most of what I've lost happened at the earlier, lower amounts.