2mg Ozempic - Anyone been there?

M

Moody_Gang53

Well-known member
Hey all,

I've been taking Ozempic since July of '25. Started at 0.5mg, then 1.0mg, and just saw my doc yesterday. I asked her about going to 2.0mg since I'm doing pretty awesome on 1.0 and haven't had any side effects. She said we could give it a shot if I want. I've dropped 33 lbs since starting, and my A1c is the best it's ever been. Started at 11 in July, now it's 6.2. Maybe a higher dose would help me lose even more and lower my A1c further.

My mom made a good point about the lack of long-term data on Ozempic at the highest dose. Anyone else have any thoughts on this? Anyone taking 2mg and willing to share their experiences?

Any opinions would be great.
 
GLP-1s have been around for 2 decades and Ozempic for almost 10, so there's actually a good amount of long-term data available. But putting that aside, has your weight loss plateaued? It's generally best to stay on the lowest effective dose because you have fewer options if things stall at 2 mg versus 1 mg. At 1 mg, you can still go up; at 2 mg, you might be out of luck.
 
If the 1mg dose is working well and facilitating weight loss, I'd recommend maintaining that dosage.
 
Thanks for the advice, @FTW and @Rene_1995. My weight loss hasn't stalled exactly, but it has slowed down a bit. That's a good point about running out of options if I jump to 2mg too quickly. Maybe I will try the 1.5mg like @Rene_1995 suggested for a while.
 
Moody_Gang53 said:
My mom made a good point about the lack of long-term data on Ozempic at the highest dose. Anyone else have any thoughts on this?
Click to expand...

I understand your mom's concern, but honestly, it's a risk/benefit thing. For some people, the health risks of staying at a higher weight or with uncontrolled blood sugar are greater than the potential long-term risks of the medication. It's a discussion to have with your doctor, and weigh those pros and cons.
 
Just wanted to add that I know someone who lost 70 pounds on 0.5 and then when they went to 1 they stopped losing. They went back down to .5 and started losing again! Bodies are weird!
 
I agree with @FTW - it's about weighing the relative risks. If you're seeing benefits at 1mg with minimal side effects, and your A1c is improving, staying at that dose might be the most prudent course of action. Escalating the dosage unnecessarily can sometimes lead to increased side effects without a proportional increase in benefit.
 
Actually found it-my mistake. Ozempic does go to 2mg. Tirzepatide showed no effect in the study though. Hard to parse signal from noise in retrospective data.
 
Found the study, turns out I was mistaken and ozempic does come in 2mg. The tirzepatide data showed nothing significant though. Parsing what's actual signal versus noise in those retrospective studies is tough, so we'll probably see more research on this question.
 
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