7.5mg - from zero to hero to...zero again?

Hong Kong Yanpep International
Just finished week 4 of 5mg MOTS three times weekly. I did four weeks of SS-31 first. Both gave me this subtle energy lift. I found myself procrastinating less on workouts and chores. Honestly expected more of a boost, might skip next round. Time will tell how much I miss the effects once I stop.
 
New to this and still figuring out sourcing. Saw places selling single vials at good prices and they claim to test. Taking a chance but turned out solid. All buying these kinds of things carries risk.
 
Microdosing made me gain like crazy. Thought my clean eating would carry me but I gained 20 in six months. Probably the inflammation relief let me eat foods I hadn't touched in years, so I just went nuts. Got cocky. Stepped on the scale after avoiding it and broke down.
 
Interesting study but wish they'd been more clear on who they surveyed. Another one I read showed older folks had way more negative views of these meds, younger people more positive. In 10-20 years GLP-1 will be everywhere and people's views will shift hard. Less judgment coming.
 
semi-positive update on the custom order situation. second shipment past customs and heading out. eta another 11-13 days so looking at six weeks total for the first order from overseas. new third party tests on one product came back not great so won't use that batch.
 
Ozempic side effects were brutal for me, constantly sick! Mounjaro's treated me way better though, at least until that 7.5mg belly injection hit different.

Been pretty consistent with electrolytes since starting all this, but slipped on that the past couple weeks, so might be worth picking that habit back up to see if it helps anything settle.
 
Noticed a huge shift in both effectiveness and side effects once I hit 5mg.

Try adjusting as much of your habits and surroundings as you do the mounjaro dose itself, you'll notice the difference.
 
Did your prescriber suggest switching brands, or did you figure that out yourself? Mounjaro seems to have quit working for me too, and I only got going back in January at the 10mg mark. Curious what app or site you used?
 
Oh my gosh had the exact same thing happen!! Had to pause for a bit, and now I'm on week two back at 5mg and it's SO much better!! Actually enjoying food again! Feels great.
 
That's not anecdotal, there was an actual peer-reviewed study published around 2024 or 2025 on this. Seen it referenced on here plenty of times. Maybe someone else still has the link handy.

Don't have time to dig it up myself, but it is documented that abdominal side effects tend to run higher for some people. More side effects doesn't automatically mean more effectiveness though. Like you said yourself, what you went through didn't end up benefiting you.

If the kwik pen is an option, starting below 2.5 might actually help. My mom did best starting around 1mg, since she lacks insurance I mix her tirz from a compounded vial myself.

Some people just don't tolerate certain meds, that's real. There are ways to ease side effects too, things like Zofran, digestive enzymes, adjusting how you eat. Sounds like another attempt isn't in the cards for you though. Sorry it didn't pan out, but Mounjaro's been a game changer for my fasting insulin, blood sugar, A1C, and other inflammation markers.
 
Not everybody can ramp up at the same speed. Reactions vary a lot person to person. Might be worth dropping back to 2 next round, or even 1.5 to 1.75. Given how rough that hit you, maybe try smaller half-milligram bumps going forward to play it safer. Hope you're on the mend!!
 
Just made the jump to a higher dose after a month at the lower one. Injection day's midweek. A little belly soreness and maybe slight nausea, but that's about it.
 
For some people, side effects just never let up.

Didn't have much nausea myself, and thankfully no diarrhea either. 2.5mg didn't accomplish anything, 5mg brought nausea whenever I ate anything, and given my schedule I couldn't fast around it (roughly 9-5 three days weekly at university), so dropped back to 2.5mg and eventually tapered off. My doctor wanted me to retry 2.5mg for eight full weeks before attempting to increase again. Took a full month completely off first as a fresh reset, and actually shed more weight during that break than across the roughly six weeks I'd already spent on the medication.

Dropping back to 2.5mg turned out to be exactly when the genuinely rough side effects started, and when I did throw up it was genuinely awful, choking on thick, barely digested food. (Sure, this stuff is supposed to work as a tool meant to make managing food easier. For me personally there were zero benefits, so obviously I kept eating the same way since willpower alone has never worked for me. Otherwise I'd still weigh 60kg instead of topping 100 at my heaviest at 165cm tall.) So took nine months off entirely.

The very first dose after that nine-month break was another 2.5mg amount. Within an hour, heartburn hit so severely I nearly ended up in the emergency room, genuinely thought it might be a heart attack, thought I was dying. Honestly had no choice but to quit for good.

Feel pretty rotten about the whole thing since it feels like I fell for something that clearly wasn't going to work for me.
 
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