7.5mg Tirz is a BEAST!

Hong Kong Yanpep International

BugTracker

Active member
Just popped my first 7.5mg shot of Tirz after two months. Seriously, zero appetite. It's a struggle to even get down a small meal, like I'm talking under 400 calories and it takes forever.
 
Maybe dial it back a bit? You could always try going down a little bit if it's too much.

Do you like protein drinks? Maybe the whey ones would be easier on your stomach than the milkier ones.
 
Funny enough, 5mg gave me the worst issues. I was nervous about upping the dose when 5mg stopped working. But 7.5mg to 15mg was way smoother. Now I'm back at 7.5mg with a tiny bit of another med added.
 
7.5mg was rough for me too. Major appetite suppression and some nausea, plus other stuff. Reducing the dose is a good call. Also, if a lower dose is working, stick with it, no need to keep going up if you're still seeing results and not having cravings.
 
I hear you BugTracker! I had a similar experience with the side effects. The first couple of weeks were awful, almost made me quit. But by week three things evened out. So glad I stuck with it!
 
Scale_Jail_Inmate said:
7.5mg hit me hard too. I went down to 6.5mg after a week, and that's been my sweet spot since last fall.

Hey Scale_Jail_Inmate I am thinking of splitting my dose into two injections per week so there is less of a “peak” effect. What do you think?
 
Just a reminder, normal blood sugar levels can feel really strange at first as your body adapts. Of course, check with your doctor to rule out any other issues.
 
7.5 mg is getting serious. Liver and pancreas are usually pretty resilient with GLP-1 dosing, but your skepticism about organ strain is reasonable.
 
I dropped seventy over seven and a half months on Tirz, stayed under five per week and now I'm at two every five days. Weight keeps dropping at half a pound weekly at this dose. Working out hard and doing TRT at the same time.
 
Took daily melatonin before starting tirz due to suspected delayed sleep phase with ADHD, just kept it up. Still on 2.5mg though so maybe it'll stop working eventually.
 
61 shots in and still not at goal with cravings coming back at what sounds like a tolerance signal is the honest long-term picture. the OP hitting 7.5mg and feeling it immediately is the strong early responder version. 20mg as the last shot before things changed is useful information - that's a significant dose and the response fading at that level is worth flagging to a provider.
 
Week 3 at 2.5mg is the early adjustment phase where most people aren't fully representative of what the medication will feel like at a stable dose. Zero appetite at 7.5mg in the OP is the effect some people hit earlier and some need the higher doses to reach. The 4-week mark at a steady dose gives you a much better read than week 3.
 
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