Anyone tried PE-22-28?

From what I understand, PE-22-28 supposedly inhibits the TREK-1 potassium channel in the brain. It's thought that this promotes neurogenesis and synaptogenesis. I'm currently taking it along with epithalon and pinealon as a stack for brain function. I think I'm sleeping better, and maybe my memory is a bit sharper, but I'm also on DSIP and selank too. I'm planning to run this for two months, then take a week off before starting a ten-day course of cerebrolysin. After that, I'll wait about a month and do a four-to-six week cycle of dihexa. I'll wait a few months before repeating the cycle. You probably shouldn't take them all together, since that could cause overactivation of neurons, possibly leading to headaches, seizures, or even worse. Theoretically I guess too much neurogenesis could cause a brain tumor. That would be awful. Oh, and I sometimes add in a dose of semax.
 
It's a nootropic peptide that acts on certain inhibitors, increasing excitability within the brain. I've been using it for a few months. It's not like taking something super strong like alprazolam. Just search it up on Google and you can read all about it. 🙂 Most domestic peptide vendors carry it. Best of luck!
 
Thanks for asking! I'm still using PE-22-28 several times a week and pinealon daily. I'm taking a break from epithalon. I'll probably start cerebrolysin pretty soon. I might wait a little longer before trying dihexa, since my cognition is normal. I'm also considering adding Cortagen at some point. Honestly, I really don't feel any different. Because many of these peptides work on gene expression, it might take a while for there to be changes. We'll see...
 
I'm injecting it sub-q. Many resources recommend a small dose, around 250mcg, so it's a pretty small dose. I've gone as high as 750mcg before. I have pretty bad anxiety, and it has gotten better since starting selank and PE22-28, so maybe it's working after all?
 
Has anyone stacked this with CJC-1295? I've used CJC-1295 with Ipamorelin. I've seen some fat loss and a teensy bit of muscle gain after about 2 months.
 
Sam_2005 said:
Has anyone stacked this with CJC-1295? I've used CJC-1295 with Ipamorelin. I've seen some fat loss and a teensy bit of muscle gain after about 2 months.
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Do you feel any different, though? More energy, better sleep, etc.?
 
I've been reading up on CJC-1295. Apparently, it can really boost your growth hormone and IGF-1 levels. Some people are reporting like a 200% increase in growth hormone. It could also help with muscle growth and fat loss...definitely researching more.
 
Charlie_49 said:
I've been reading up on CJC-1295. Apparently, it can really boost your growth hormone and IGF-1 levels. Some people are reporting like a 200% increase in growth hormone. It could also help with muscle growth and fat loss...definitely researching more.
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I saw one person say they haven't even been sick since starting peptides – ipamorelin/CJC-1295. Maybe I should look into this more...
 
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