Battling the Nausea Rollercoaster

This happens even at the start dose. What helped: avoid fried, sugary, processed stuff. Force yourself to eat tiny portions — like one-eighth of normal — every couple hours. Nausea gets worse without food. Fluids matter a ton. Ask your doc for Zofran if it's bad. Reading through the threads here helps a lot.
 
Just did dose 2 end of April. Yeah, nausea hit me but I used otc stuff for it. Biggest issue is eating too much at once — soon as I feel full I stop. Been taking the anti-nausea med an hour before dinner and it helps a ton. Haven't thrown up tho.
 
felt some effects within hours. made sure to eat after dosing so i wouldn't get nauseous or headachey. the first day had tiredness, muscle soreness, heartburn, nausea, but by day and a half i felt okay again.
 
Week one nausea at 0.25mg tends to be the worst of it - the waking and post-meal pattern resolves over the next two to three weeks as the dose stabilizes. Small meals and avoiding high-fat foods alongside the ginger is the standard approach.
 
The PPI addition for GLP-1 nausea is more reliable than most people expect - the increased acid sensitivity that comes with slowed gastric emptying responds well to proton pump inhibitors, and many people find a short course at dose escalation prevents the worst of the gastric symptoms.
 
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