Cagri dosing: share your protocol!

ThinFixed853

Well-known member
Hey all!

I made another post but I didn't see a good dosing guide for Cagri anywhere here. So I figured I'd put one together! This isn't gospel -- adjust as you see fit! If your protocol is different, please share it in this thread. I'm open to anything!
 
Starting my first injection tomorrow! This chart really helped me out with reconstitution since the numbers are kinda weird. Quick question though: I'm using regular bacteriostatic water, not the acidic kind. How long can I keep a vial in the fridge? According to this, I won't finish the 5mg vial until week 12, which is like two and a half months. But I've seen a few comments that say to toss it after a month. What do y'all think?
 
Hitting tiny doses like 5 or 10 units seems like it'd be tough to get right. Seems like there'd be a big margin for error, no?
 
Yep, @Gym_Taco, bacteriostatic water is pretty safe. I personally add lots of bac water if I'm using a small dose. It makes the math easier. Also, consider starting with 0.125mg.
 
I agree with @Funky-King. I use 2ml of bac water for every 5mg of Cagri. Makes the math simple. 0.2ml, or 20 units, equals 0.5mg. 10 units for 0.25mg. 5 units for 0.125mg.

If you only used 1ml of bac water, then you'd be at 2.5 units for a 0.125 dose, which would be difficult to measure correctly.
 
Adding more diluent, like @Jamie2003 and @Funky-King mention, is a common strategy to reduce dosing errors when working with highly potent compounds. It's especially helpful when using standard insulin syringes, which have inherent limitations in accuracy at very low volumes.
 
I'm curious if anyone has experience with cycling back down to a lower dosage after being on a higher one for a while? I've heard anecdotally, and read stuff online, that sometimes your body can almost 'reset' its sensitivity. Like
ThinFixed853 said:
do whatever works for you
but its like... the lower dose can become effective again?
 
That's interesting, @ToneLean. I hadn't heard that, but it makes sense. I'm all about experimenting to find what works best for each person.
 
What about splitting doses? Has anyone tried that? I've been on 1mg for a while now and it tapers off by the end of the week. Thinking about trying half the dose every few days.
 
I did split dosing with sema when I was moving up in dosage to reduce side effects. It worked great for that. Never really noticed if it helped with weight loss, though.
Gym_Taco said:
Thinking about trying half the dose every few days.
Just be careful if you split it *too* much, you'll end up lowering your overall weekly dose!
 
I wanted to add to the discussion on split dosing. I agree with what's been said so far. It can definitely help mitigate side effects as you increase the dosage, and the evidence suggests that it may provide more consistent appetite suppression throughout the week for some individuals.
 
Just got my first shot in at 0.25 yesterday. Curious what worked for you - like how you titrated it and whether exercise made a difference. I'm aiming to drop about 45-50.
 
I'd say that's true, but I want to share my own path. Three months on this. First two at 2.5, now switching to 2.5 every four days. Keeps food noise down better versus the weekly schedule the manufacturer recommends. Maybe find your balance where you don't rush titration up. Find your minimal working dose and stay there. Keep tolerance low so you can potentially quit eventually. Also read around here - amazing stuff on other peptides. Got some smart people finding combinations that really boost results.
 
Every protocol is totally made up and spread through the telephone game. Need to answer key questions. What actual human studies exist? What dosing? Why those dosages? Who was studied? What were positive findings? What side effects are possible? What's your reason for specific dosing? Is that reason real? Is it real for this specific peptide? Until you answer these, how can you seriously inject something you don't understand?
 
Study design seems silly given half-lives. Who wants alternating normal versus crave/binge weeks? Appears designed for expensive autoinjectors versus optimal maintenance protocols.
 
was 358 when i started in february at 2.5mg, took it before bed and had to force myself to eat the next couple days. felt it hard for over 48 hours, then some for 6 days. now at 7.5mg and down 25ish pounds, don't feel it till day 3 or 4 and it only lasts a day or two.
 
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