Cagri with my Reta - good idea?

Hong Kong Yanpep International
Been on reta for close to a year now. Currently at a moderate weekly amount, was higher before but side effects got to be too much. Started in the low 200s, dropped a solid chunk over about half a year and then plateaued. So now a small amount of a second compound got added in too, and the number's held steady at a lower point since.

Feels like it dulls desire across the board a bit, food, alcohol, exercise, everything takes a small hit. But bloodwork's looking great these days and hoping for another good chunk lost before eventually stepping down both and settling at a low reta amount long term.

Then maybe with a smaller dose, energy and motivation for things will come back up to normal levels.

Though maybe not wanting to do yard work today has more to do with the heat than the medication.
 
Curious, has your dosage stayed fixed for over twelve months straight? I've been running the identical reta amount for nine weeks now, right from when I first started, sitting at 1 mg weekly. Just last week, actually, I added cagri at 266 mcg. And weirdly enough, that same reta dose seems to be hitting harder now compared to when I first began. Suspect the same pattern will play out with cagri eventually too. So I'm pairing cagri alongside reta, but my guess is the effect won't fade over time. Doesn't seem like the body actually builds tolerance to this. Haven't come across anything in published research confirming that either way. But clearly this differs a lot from person to person.
 
Climbed reta dosing clear up to 12mg once weekly, hit a wall for several months, eventually decided to drop back to 6mg and add cagri into the mix. Better to hold onto what's already gone than throw in the towel, and there's been additional loss over the last half year on this new setup. A gentler pace just seems more manageable for the body to settle into as its new baseline.
 
Honestly whether you split it up or take the whole thing once weekly comes down to personal preference. I'm currently at 8 mg, splitting it into 4 mg Sunday and 4 mg Thursday, mainly to ease nausea and diarrhea rather than for better hunger control.
For appetite specifically, I'd lean toward adding a small Cagri dose instead. Your system adapts more the further into Reta you get, meaning even bumping the weekly amount up won't necessarily bring back that same early hunger control you felt at the start.
 
Reta at 8mg gives me no appetite suppression whatsoever, and going higher triggered allodynia. A few months back cagri joined the mix, now up to 2.7mg. Together with 8mg of reta, that hits my ideal balance. My weekly weight stays 204-209 while I still manage the protein needed for muscle and energy. I can tell which peptide to raise or lower depending on my aim: a bit less cagri to bulk, a touch more reta to drop several more lbs.
 
Cag began for my wife last Thursday, .25mg. Her reta is 8mg and it goes in on Mondays alongside. My own Monday reta pin is 4mg, and I've considered starting cag Friday, .25mg, though the possible fatigue worries me. Quieter food noise appeals to me, yet I need room to eat enough protein. I flip-flop on it daily. When I tried 6mg of reta, gut trouble hit hard.
 
Just one person's take: when I moved to maintenance at goal weight on 5/25, I cut Tirz from 15mg down to 10mg within 2 weeks and added .125 cagri. The next week I stopped Tirz completely and began 1mg Reta with .25 Cagri. The Cagri was there in case food noise got unbearable (there wasn't any, just normal hunger, it's simply my body asking for fuel). Within a month I moved up to 3mg Reta. I quit Cagri in 11/2025 because I'd accidentally lost 15 lbs more than I wanted during maintenance. I remain on 3mg Reta weekly, weight stable. I think Cagri is a great add-on when you need a small push toward goal that higher Tirz or Reta alone can't manage.
 
Hi, I'm new here. About 2 months on Reta, went 2, then up to 5mg, barely any effect (I also didn't respond to name brand tirz). I see lots of people starting or adding cagri at 6mg reta and wonder if there's a reason for that dose. Should I keep raising the reta by itself a bit longer, or bring cagri in already? Appreciate any input.
 
1.5mg isnt high, its basically the lowest therapeutic level once titration ends. I would move up a step rather than bring in a second or third drug to fix a small dip in suppression late in the week. If the trouble is just food noise coming back on days 5-6, try splitting the reta into two shots or dosing every 6 days. On stacking, reta with cagri should be fine together, while sema would be excessive and carries the biggest chance of side effects. My own weekly stack is 2x4mg reta (Mon/Fri) plus 2x3mg tirz (Wed/Sun).
 
You must log in or register to reply here.
Back
Top