Crazy dosing schedule!

Hong Kong Yanpep International
Good on 1.0, moved to 1.5 a month ago. Side effects are nasty — constant sulphur burps, bloating, stomach pain. Lost 40 lbs on the schedule up to 30 units over months. Hunger was easy before, going back to 1.0.
 
Been at 210 myself, so I feel this. Hit my first plateau around week 3 - appetite suppression didn't kick in until I was steady at a higher dose. For me, staying put for a few weeks made sense before jumping up. My doc said the body needs time to adapt. You're doing great with the workouts - that matters. Keep the dose steady and see if week 6 brings the shift you're waiting for.
 
Inconsistent dosing makes it hard to know whether the response is from the dose or the variation. Standardizing to one known amount for a few weeks before titrating gives cleaner feedback.
 
The end-of-pen boost from the overfill is worth doing if the pen allows - the residual in the mechanism after the last full dose is real and not negligible. Whether you're drawing .25 or .50 the math on what's left over works the same way.
 
Starting at 1mg and stepping up through 2mg is a really sensible titration pace. The results not matching expectations at 2mg doesn't mean much yet - the first couple of months are usually more about adjustment than dramatic movement. Give it another full month at the higher dose before drawing conclusions.
 
The stated mg versus tested dose question comes down to how confident you are in the specific batch - if you have independent testing on the lot you are using, the tested figure is the more reliable basis. For untested batches, the stated figure is the only reference available.
 
Locked into a steady 12mg weekly total, splitting it into 6mg Monday and 6mg Thursday. Just sharing this as an example for anyone still climbing their dose or splitting vials with someone else.
 
Went through the whole sub searching and still can't crack this one! Is it basically underdosing slightly so you end up with leftover for a bonus dose? Or just fewer clicks overall?
 
Honestly the numbers just worked out that way, cleared my whole stock the same week. Ran that same protocol last year but bumped up the doses and stretched the length this time. First time trying 5-Amino too.
 
Does anyone actually know the full story behind those six cases? Read somewhere that one of them started right at 12mg, and was dosing twice weekly on top of that.
 
Hi! Do you prefer splitting doses on set days, say Tuesdays and Fridays specifically, or spacing every three days with the actual calendar dates drifting over time?


Curious which method you lean toward and the reasoning behind it.
 
Appreciate that. Read elsewhere that it's only good for four weeks before tossing it, which sent me into a bit of a panic. Ended up ordering the larger size since that's all that was available, and running just 1mg weekly means a lot would go unused.
 
Wouldn't dosing once at the start of the week and once at the end technically land on the same day again eventually? Ha.

Plenty of people around here inject twice weekly, more commonly landing on day three and day seven or thereabouts. Goes by the name split dosing, and it keeps drug levels steadier overall. Some claim it holds food noise at bay more consistently and eases side effects too.

Never tried splitting mine personally, mostly because early on I came across something suggesting it was less effective, though I'm not fully convinced that's actually true. Just kind of lodged itself in my head like a myth that won't shake loose. I stick with one weekly shot purely for simplicity.
 
Based on what's documented, at low amounts this compound carries roughly a six-day half-life, so splitting the dose just means it takes longer to build toward higher blood levels, but ends up maintaining a higher baseline overall compared to a single weekly injection. Might be worth revisiting how this mechanism actually works.
 
Short version: I can hardly imagine worse dosing advice for MJ. Levels accumulate across at least 4 weekly shots, and week four on a dose can feel wildly unlike weeks one to three. The 2.5mg to 5mg step trips up many people since it's the one jump where the load truly doubles. And you never reached the 2.5mg's full effect (roughly half the load), so what you'd feel is well over double. Plenty of people get away with it, yet it's a huge gamble. My own move to 7.5mg happened following 20 weeks at 5mg (plus a 4 week 2.5mg start), and I had zero side effects after my first 3 shots at that dose. The slow, patient route worked, so I'd never recommend rushing it.
 
Ha, no luck then. Was looking for some secondhand medical advice :) From what I know Lilly has trials running at 20mg and 25mg, so it wouldnt have seemed odd to me if your doctor told you to go a bit higher, or to spread it over a five to six day interval.
 
Yes, that's the overfill. In Australia we only had vials for over a year, then the KwikPen arrived and the vials were discontinued. Support groups filled with complaints that the KwikPen was weaker than vials. It turned out that drawing 65 units from a 5mg vial gives you actually 6.5mg, nearer the 7.5 mark than the 5, so people had unintentionally stepped down a dose. Skip the extra liquid unless you mean to move up to that level, and definitely not on a 15mg vial.
 
Ten mg went in last Sunday and 3.3mg this Sunday. If you aren't sensitive and side effects are minimal, you've had 10mg in your system for weeks, and I haven't run the math. With a Friday delivery, take roughly 6-8mg that day and the remainder Monday, resuming normal timing the Sunday after. A Tuesday arrival could mean 6mg Tuesday, then 10mg Monday with a 2mg top-up around Thursday or Friday, Sunday as usual after. The main thing is not to rocket your peak beyond where it's been. My own style is split doses, quick titration and few side effects, so easing back in with split doses suits me.
 
ya my vials are 5ml sterile ones, i run four of them.. knowing this now lets me measure doses for the wife, my sister and me more accurately. the whole batch seemed a bit weak to us. being almost ten percent light of what i assumed was noticeable, though not by much, and we all felt like adding a unit or two was needed (my math then was 0.227mg/unit). reason im forever lurking here.. id have written it off as a slightly underdosed batch, tacked on a couple units and moved on. three vials went into one with 4ml of water, and sloppy assumptions put the math off by 0.021mg/unit (three people get three different amounts so dose per unit gets calculated each time). my sister and i react strongly to drugs, i dropped roughly 90lbs on 2.5mg tirz.
 
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