WellWin
Well-known member
START WEIGHT: 257 lbs || CURRENT WEIGHT: around 160
Started in size 20/22 pants, XL shirts. Now in size 10 pants and medium shirts.
I finished my participation in the Novo Nordisk STEP-UP trial on July 5th. It was testing 7.2mg injectable semaglutide against placebo and the standard 2.4mg dose. I had a 1 in 7 chance of placebo; 3 in 7 of 2.4mg; and 3 in 7 of 7.2mg. Double-blinded, so I don't know my dose until late 2025 when they publish the results.
I started in mid-Feb '23, and increased the dose every month (assuming I wasn't on placebo, which i doubt). By July '23, I was either at 2.4mg or bumped up to 7.2mg. I stayed there until Jan '24, when I told them I was worried about lack of appetite, hair loss, and my period stopping. They dropped me to 1.7mg, which I've been on since.
I didn't track kcals. I have a bad history with it. But if I'm experimenting with a new recipe, I'll add up the kcals, protein, and fiber to see if I want to adjust (and then never look again). I try to eat more protein, fruits, veg, and beans. I eat out and drink occasionally.
I met their exercise goals already (powerlifting 3x/week and softball 1x/week). I kept that up through the trial, plus volleyball for about 6 months.
My worst side effects were constipation (still dealing with it) and some nausea with dose increases. The benefits are worth it. My food noise on 1.7mg is maybe 10-20% of what it was, depending on the day. Just enough to make me think about wanting something sweet when I'm stressed, but not overwhelming. The lower food noise is the biggest benefit, plus improvements in my IBS, skin, and more.
The trial has a 9-week washout period, with a follow-up to check blood levels (to make sure the 7.2mg dose is cleared out).
I'm working to get insurance to cover brand-name after the washout. Plan is to maintain at 1.0 or 1.7mg. I was automatically denied because my BMI is around 25-26, so they said no. We're appealing, hoping a human looks at it! haha
Ask me anything about the trial, semaglutide, food, exercise, whatever! I'm grateful for the trial and hope I can continue after the washout.
Started in size 20/22 pants, XL shirts. Now in size 10 pants and medium shirts.
I finished my participation in the Novo Nordisk STEP-UP trial on July 5th. It was testing 7.2mg injectable semaglutide against placebo and the standard 2.4mg dose. I had a 1 in 7 chance of placebo; 3 in 7 of 2.4mg; and 3 in 7 of 7.2mg. Double-blinded, so I don't know my dose until late 2025 when they publish the results.
I started in mid-Feb '23, and increased the dose every month (assuming I wasn't on placebo, which i doubt). By July '23, I was either at 2.4mg or bumped up to 7.2mg. I stayed there until Jan '24, when I told them I was worried about lack of appetite, hair loss, and my period stopping. They dropped me to 1.7mg, which I've been on since.
I didn't track kcals. I have a bad history with it. But if I'm experimenting with a new recipe, I'll add up the kcals, protein, and fiber to see if I want to adjust (and then never look again). I try to eat more protein, fruits, veg, and beans. I eat out and drink occasionally.
I met their exercise goals already (powerlifting 3x/week and softball 1x/week). I kept that up through the trial, plus volleyball for about 6 months.
My worst side effects were constipation (still dealing with it) and some nausea with dose increases. The benefits are worth it. My food noise on 1.7mg is maybe 10-20% of what it was, depending on the day. Just enough to make me think about wanting something sweet when I'm stressed, but not overwhelming. The lower food noise is the biggest benefit, plus improvements in my IBS, skin, and more.
The trial has a 9-week washout period, with a follow-up to check blood levels (to make sure the 7.2mg dose is cleared out).
I'm working to get insurance to cover brand-name after the washout. Plan is to maintain at 1.0 or 1.7mg. I was automatically denied because my BMI is around 25-26, so they said no. We're appealing, hoping a human looks at it! haha
Ask me anything about the trial, semaglutide, food, exercise, whatever! I'm grateful for the trial and hope I can continue after the washout.
