Dosage jump too big?

[bye-bye-binge]

OK so I'm in week two, and the schedule says I should inject 0.22 ml (that's 22 units, right?) for these first two weeks, but then jump to 0.44 ml (44 units) in weeks 3 and 4. Am I crazy or does that seem like a huge leap?

 

[bye-bye-binge]

did you have much nausea starting at 22 units?

Honestly, not really! I was expecting to feel awful, but so far, so good. Maybe I should just stay at the lower dose longer like some people are saying...

 

[Happy_Mode]

Wow, that's a lot! I started at just 8 units and stayed there for a month and a half!

 

[Moody_Gang53]

I'd definitely stick with the initial dose for at least a month before thinking about increasing it.

 

[OldPath695]

My doctor told me to only increase by 5 units each week MAX, and only if I feel like I need it. If I'm doing well on my current dose, she said to just stay put. I started at 10 units (0.10 ml) and slowly worked my way up to 25 units (0.25ml) over about 3 months.

 

[SaladLife]

Units can be tricky, it depends on how your medication is measured. When I first started, I had to contact the pharmacy to double-check my calculations to make sure I was dosing correctly.

 

[ScaleHater]

Yeah, I'd definitely double-check those instructions. That does seem like a big jump!

 

[Sassy_Good]

I'm such a lightweight, haha. I just started and my very first dose was only 3 units (250mcg). @bye-bye-binge, did you have much nausea starting at 22 units?

 

[Moody_Gang53]

Following up on @OldPath695's comment about slow increases - that's what I would suggest, too. Gradual is always better than shocking your system. Listen to your body!

 

[ThePal]

I've heard of people using expired pens with no prob. If it's clear and was in the fridge, it's probs fine.

 

[Happy_Mode]

I agree, I think a smaller increase might be a smarter move. I know it's tempting to rush the process, but slow and steady wins the race, right?

 

[OldPath695]

Adding to what @ThePal said, while I can't give medical advice, my pharmacist mentioned that if stored properly, these meds are often good a bit past the expiration date. But clear liquid is key!

 

[plot-twist]

Some days I hurl, some days I don't. Usually hits one or two days after my shot or just nausea for a bit. Once I'm empty I'm fine. Rinse with water and move on. Don't brush your teeth after though—acid wrecks them. Water or baking soda rinse instead.

 

[melon_readerhq]

Meal prep is basically a hack on this medication. Made huge shifts for me too with my current script.

 

[smoothie-tracker]

Big jumps usually cause trouble for a week or two. Sounds like he's already pretty fit and active, so no need to rush the dose escalation. Dude's crushing it with the exercise routine.

 

[HealthLoss]

search for [site: glp1forum] and whatever you're looking for.

 

[plucky_lowkey4599]

That's solid progress for sure. Don't think you need to chase more loss - what you've already done is a big accomplishment.

 

[pretzel-sema29]

I keep my details in recurring calendar events so I don't lose track. Helps me remember what I'm using, the vial size, my dose, pin volume, and when I reconstituted it. So far: T30, 7.5mg per 0.1ml, mixed on 04.20.2026.

 

[pretzel-sema29]

Big time, but I drank too much and flushed everything out. Last two blood work showed low sodium and chloride, I was dehydrated. Now mixing Liquid IV sticks in Gatorade and having one daily. Turns out all that water while dieting flushes the good stuff. Don't overdo the water.

 

[InsulinResistanceGuy]

Mid-ramp dose doubles are a common early stumble - the side effect window hits harder than the initial dose.