Down 70lbs, but now what?

Hong Kong Yanpep International
SaladLife said:
Has anyone else been dealing with constipation? I'm drinking tons of water, but it's still an issue.
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Water and fiber are key! I'd also suggest a fiber supplement or even some prunes. Good luck!
 
GLP-1 GI at the outer edge includes bile acid changes from rapid loss and motility slowdown. Worth a GI doc visit if it's been more than a couple weeks.
 
What's your maintenance plan looking like? Curious if you cut the dose down to keep weight stable, or held the same dose. I'm 5 lbs from my goal and trying to figure out the taper question now — my doc says we'll go down to 5mg from 10mg but timeline is fuzzy.
 
Had the same baseline - Miralax before starting, Miralax still after. Now it's Miralax plus milk of magnesia a few times a week on top. Gastroenterologist suggested it after nothing else worked. Tried the standard stuff - fiber, water, walking. This combo is the only thing that's actually helped. Might end up needing a prescription.
 
70 lbs to goal is the full arc - the now-what question usually lands on maintenance dose, which most find lower than what got them there.
 
The gallstone development at 70lbs is well-documented as a fast-loss complication rather than a medication effect - the rapid shift in bile composition during accelerated fat breakdown is the mechanism. Managing post-loss maintenance on the drug side while dealing with the gallstone recovery is the harder coordination problem, but it is workable.
 
51kg of weight loss on a path through multiple surgeries and still going is a remarkable demonstration of persistence. The gallbladder connection to rapid GLP-1 weight loss is well documented at this point - the rate of loss seems to matter as much as the total. Did the surgical team make that connection or was it just discovered coincidentally?
 
8kg up that you know isn't water or cycle-related is a hard realization to sit with. 70 lbs down is still a massive result and the constipation on Mounjaro making things more complicated is a real side effect that doesn't get enough attention. What's the current dose situation and have you tried adjusting anything for the constipation side?
 
The gallstone-before-Mounjaro history is actually the more common pattern than people expect - rapid weight loss can increase gallstone formation, but pre-existing gallstone disease is also very prevalent in the population that presents for obesity treatment. Distinguishing which caused which matters for the surgical conversation.
 
Look up ursodiol, probably the medication prescribed to dissolve gallstones. It's real, just slow, so only a later scan will tell if they shrank. Fast weight loss on mounjaro can cause stones to form or make existing ones troublesome, hence the genuine pancreatitis risk. Your endo was aware of the gallstones and recommended mounjaro anyway, so you're not in unexplored territory. Certain people start glp-1s despite having gallstones, watched closely with an ultrasound every few months. Have your doctor outline a game plan that does not need surgery immediately, as taking out a gallbladder isn't trivial and the stones could remain silent when loss is gradual.
 
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