First week - Feeling hopeful!

[CutFWIW]

super responder here. lost 100 lbs in 6-7 months and kept it all off. changed how i eat completely since starting. food noise is gone, eating small meals throughout the day instead of all day grazing. a1c is normal now. feels amazing honestly.

 

[Kate_Notes]

First week is special. You're still figuring out what's normal and what's just your body recalibrating. The noise quieting down hit me hard early on too - I remember eating half a plate and genuinely not wanting more. Then I realized I'd been eating past fullness my whole life without knowing it. That shift, more than anything, made me think this was actually going to work. Stick with it.

 

[LeanWine]

The first week being water-heavy is the norm, especially with the low-carb switch. The actual fat loss rate shows in weeks 3-6 once glycogen levels settle.

 

[Gene_Pizza]

Day one appetite response is more common on tirz than sema - the dual mechanism hits faster for a lot of people. Half a kilo weekly is a reliable pace that holds better than faster starts because the metabolic baseline stays stable underneath it.

 

[hazy-shakerirl]

Climbing and running mix is great - low pressure about food choices too. Simple routines often work better than rigid plans anyway.

 

[Blair]

End-of-week appetite creep is the standard signal that the dose hasn't fully locked in yet - most people find it normalizes by week 4-6, and the ones who don't usually benefit from splitting the dose into twice-weekly injections rather than bumping the amount.

 

[VegasVolcano]

17 in three weeks is strong - the first-week number is usually water but weeks 2-3 showing it too means the appetite effect kicked in.

 

[Inject_Gal]

First week side effects are often the worst it gets - the body adjusts over the following weeks and most people find week three or four looks very different. Hanging in is the right call at this stage.

 

[downsize_vibes]

Feeling that hunger return toward the end of the week at 1mg is totally normal - it's just the dose wearing off. Staying put and letting your body adjust at each level is the right call. The cravings settle down a bit more each week for most people.

 

[saltynoodle59]

congrats on the loss - the first week difference in the OP is not universal. a lot of people don't feel anything the first week, or even the first month. the stuff builds up gradually and for some it takes 3-4 weeks at a consistent dose. if appetite hasn't changed by week 2-3, worth noting for the next check-in.

 

[cocoa_roaster]

The stress and boredom eating connection is real and it's one of the things the medication addresses most directly. When the food noise goes down, snacking from habit or emotion drops too. The walking plus low calorie approach people are sticking with here is solid - adding resistance work on top of that is what protects the muscle through the loss.

 

[smoothie_roaster87]

5 weeks in and the body adjusting to the first dose level is the pattern everyone hits. The first week's quieter hunger is real but the body adapts. Moving up when that happens is the titration response and it usually brings the suppression back. How much did you adjust at week 5?

 

[grumpywanderer]

Sounds like a really solid start honestly. That early shift in appetite can feel weird at first, but keeping notes on appetite, protein, hydration, bathroom habits, and any side effects as you go really helps you see what's actually shifting week to week.

 

[salty-sorter]

Week one feels different when it's actually working, just make sure protein's covered whenever you do eat, matters even more with portions running this small.

 

[bagelpeeler-13]

Welcome, and good on you for taking that leap. Early days often bring queasiness, so stick to smaller meals, drink plenty of fluids, and try to be gentle with yourself, benefits usually build up gradually over the following weeks, but you've got this!