Food noise creepin' back!

ive been running 17 to 18 mg weekly and the appetite control is legit. been at this level for a couple months. my original plan was to push toward 20 or 25, but then i added semaglutide six weeks back. at 1 mg sema now. figured id dial back the tirzepatide as i ramped up the sema, but honestly havent needed to
 
settling my Tesa/IPA stack now so it's solid before i tackle mitochondria peps next month. want dosing locked in first so i can isolate and measure the mitochondria work clearly.
 
After 18 months the GI stuff stops, food aversions gone, weight loss pauses. Ozempic still works on A1c, kidneys, heart, liver, gut motion, weight hold though. Feels more or less effective depending on where you are in titration.
 
running a tesa/ipa blend on my own protocol. two mg tesa plus about 545mcg ipa per pin. it's spicy enough for glute pinning, stings a bit, welts for a while. mixed 2ml bac into a 10mg vial, so 2mg is 36 units.
 
Yeah I'd pay more for that. Close to maintenance and an amylin agonist with fewer side effects seems like the smart move to lower my doses on the other stuff. I'm in.
 
Five months in and food noise being gone was the best part - didn't realize how loud it was until it actually stopped. Stacking reta and tirz together is less common talk but it's out there. Takes some digging to find what other people have tried and how it actually worked for them.
 
Reta works differently than the others. Weaker appetite suppression which people overlook, especially bodybuilders chasing muscle. The binding strength matters - less means less food noise control but maybe more metabolic freedom for building. Depends on your goal. Excess fat changes the equation.
 
Kept my dose low and only went up when the hunger crept back. Spent most of my time at the same level - weeks of stability before moving. Dropped 77 pounds slow and steady, then came back down the same way. At my current maintenance dose the appetite's starting to whisper again so I'm holding here.
 
Food noise coming back is so real. I had the same thing happen around month three. Timing my dose closer to when the cravings hit helped, and going back to counting calories again made a difference.
 
I hear the frustration. Food noise creeping back would push me to adjust too. For what it's worth, switching to a 6-day interval worked better than upping the dose itself - kept things more stable for me. Three weeks of tracking will tell you if it's the stack or just adaptation. Don't jump too fast though.
 
The late-week hunger return is a clear signal your trough arrives before the next dose. Shifting the frequency to every 6 days closes that gap before appetite has time to rebuild - the cleanest response to that pattern.
 
Food noise returning after a year at 1mg is the dose plateau signal - a step-up to 1.5mg or 2mg usually brings the suppression back within a few weeks.
 
The day 4-5 hunger return at the starter dose is consistent - the suppression window with 2.5mg is narrower, and the gap shows up around where yours did. Getting full faster is the signal that holds. Food noise at day 4-5 tends to moderate as the dose escalates. Nine doses in with it returning at 5mg is the escalation indicator - this dose has given what it can.
 
Back
Top