Gaining weight back on Ozempic!?

big-mood

Active member
I've been taking Ozempic for around 5 months. I went from 280 pounds to my lowest of 240. I just weighed myself today and I'm up to 248 pounds. What gives? I haven't changed my diet; if anything, I've been eating cleaner. I'm worried I'm developing a tolerance. Is that possible?
 
Are you working out more? If you are, you might be gaining muscle. When I was training for races in the past, I put on ten pounds of muscle but went down a size because muscle is more dense. It's important to consider overall fitness and well-being instead of just the number on the scale.
 
Without knowing more about your diet, it's likely water weight. Stop stressing about daily fluctuations. Weigh yourself every morning after you wake up, then average it out over a week. Use that weekly average as your weight. As you lose weight, your body changes, and many things can influence the scale. Don't panic over small changes. If you see consistent gains over a month, then reduce your calories a bit. This is a marathon, not a sprint.
 
I've been on Ozempic for like, six or seven years now. I have type 2 diabetes and PCOS. The first couple of years, I didn't see too much change on the scale, though my numbers were better. I couldn't get below 220. I was exercising and doing what I was supposed to. Then some stressful stuff happened, and my anxiety meds were increased. That was a disaster. I basically became a human garbage disposal 30 minutes after taking the medication. I stopped taking it and started smoking weed. I then lost about 20 pounds in a month while caring for my Mom. Then another 50 over the next few months. In the last year, I lost another 20, but my blood sugar got too low. I gained about 15 pounds since dropping from 2mg to 1mg. Slow and steady wins the race! Also, lift weights! You're losing more than just fat. Take your vitamins, too. My hair is getting thin.
 
It's probably just water retention. Salty foods can cause that. Or it could be inflammation. Weigh yourself a few times a week to track your progress. If you see similar numbers a few days apart, then worry. You also might need to increase your dose.
 
Do you weigh yourself at the same time of day? Weight can fluctuate rather easily, mostly due to water. To gain 8 pounds in a week, you'd need to eat around 24,000 extra calories, or over 3400 calories a day. If your BMR is around 2200 calories, you'd have to eat about 5600 calories per day to gain that much. Are you tracking your daily calories? Muscle weighs more than fat, so if you're working out and eating more protein, you could be replacing fat with muscle.
 
Okay, let's think about this. Ozempic slows down digestion, right? So... 1. Are you constipated? 2. Is the medication still working besides the weight fluctuations? 3. Are you about to get your period? 4. How's your water intake? Eating a lot of salt? 5. Working out? What kind?
 
Unless you ate an extra 25,000 calories above your TDEE, you probably didn't gain 8lbs in one week. Did you weigh yourself at a different time, location, or wearing different clothing? Do you menstruate? How long has it been since you changed the scale's batteries?
 
Age matters a lot. Younger skin bounces back especially with peptide support. I'm middle aged with less to lose and just started GLP1 plus another peptide. Nothing yet but planning to switch soon. Hopeful the extra support helps with any stomach sag by goal weight.
 
Weight fluctuates. I fluctuate up, down, up, down, then I lose weight. It frustrated me at first, but I've realized it's just my body and have accepted it.
 
How are people losing so much weight in just 20 weeks? Like, forty pounds in five months? I only dropped about 30 in a year. If your dose is higher than mine, you must be throwing up all the time due to reflux and nausea. I'm already nauseous a few times a week on a lower dose. How are the side effects not unbearable at a higher dose? I see people lose over 100 pounds in a year, and I don't get it 'cause you still have some appetite on this medicine. It’s also not healthy to lose weight that fast. About two pounds a week is normal. People dropping so much so quickly may end up with loose skin.
 
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