GLP-1 dose weirdness?

ScaleSlayer88

ScaleSlayer88

Active member
I've been scratching my head about this for a bit and wanted to see if anyone else has run into something similar. I started with a weight loss clinic using their pre-packaged stuff, then switched to a local compounding pharmacy to save some money.

This is where it got strange. Their only concentration option is 16.6mg/mL. My doc prescribed 2 of these, making my initial vial 33.2mg in 2mL.

I figured out my dosing, but I can't understand why they'd use 16.6mg, especially because most vials seem to be 5, 10, or 15mg. What's with the odd number? Anyone have any ideas?
 
That is quite peculiar. I'm wondering if they acquired a batch of 15mg vials that tested slightly higher, around 16.6mg, and that's their workaround. It's the only thing that comes to mind.
 
That's a thought, but considering the reports from earlier this year about 15mg vials being underdosed, maybe these are just 2 slightly weak 10mg vials. Haha!

I'll see if my NP knows anything; she's been using this compounding pharmacy for a while.

I'll let you know if I find out anything.
 
I actually mix mine similarly. There are several of us on different doses, and it makes the math easier for folks. All doses are under 1 ml.
It’s 15, 30, 45, 60, 75, and 90 units.
 
Those are good dose examples - your math/explanation is spot on!

So, dosing is simple, but I guess you need a precise tool to initially create the compound, which you have. I won't be trying that with my kitchen scale. 😂

Thanks!
 
Compounding pharmacies often use unconventional dosages with GLP-1s because the legal loophole enabling them to offer their services hinges on the patient needing a specific dosage that isn't available through conventional pharmaceutical channels.

When I first started compounded sema, my doctor's titration schedule was all over the place, like .2, .4, .6, 1.12, 1.9, 2.16, 2.3 mg/week. They expected me to inject 6.7 units. Seriously? They know people are adjusting dosages themselves as they provide enough in the vial for more flexibility. It's like how supplement shops make you click a button saying you won't use the product for human consumption.
 
I started my GLP-1 journey five months ago, and I'm loving the results! I'm seeing and feeling such huge improvements. It's amazing how things can change in such a short time.

My doctor is suggesting a bump up to 5mg, which sounds great since the food chatter is creeping back in, and I'm feeling hungry again on 2.5mg now.
 
ByeByeBackfat said:
My doctor is suggesting a bump up to 5mg, which sounds great since the food chatter is creeping back in, and I'm feeling hungry again on 2.5mg now.
Click to expand...

It's usually best to stick to the lowest effective dosage. Have you considered staying on your current dose longer? If weight loss stalls at a higher dose like 2mg, your options become limited.
 
That's a great point, LBM_hacker! I'm still on 2.5mg and started back in October. The food noise is starting to come back, but I actually like that feeling. It's giving me a chance to practice dealing with it before moving up to a higher dose.

Whenever I feel the noise, I drink water, and it goes away. I think this is a great way to build better habits.

Now that I'm eating a little more, I'm also exercising more. Trying to build that into my daily routine.
 
ByeByeBackfat said:
My doctor is suggesting a bump up to 5mg, which sounds great since the food chatter is creeping back in, and I'm feeling hungry again on 2.5mg now.
Click to expand...

Congrats on the improvements. I'd say go for the increase to 5mg! I was able to lose a significant amount of weight and feel great on that dose. The food noise and hunger were completely gone for me.
 
The 30mg/ml concentration ceiling for GLP-1s is a practical anchor - staying below that threshold keeps viscosity predictable and injection volume in a workable range regardless of which pins you have on hand.
 
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