Honestly my telehealth sema feels padded? Laced? Not sure what word fits, but it does nothing compared with other glp1s. I raised the dose and still see no effect. It's like injecting saline or something.
Sema was a bust for me: constipation from hell, fatigue, and the scale never moved. Then Zepbound, which is Mounjaro under another name, worked great with much milder side effects. It only started paying off big once I got to 7.5mg.