Not a doctor but if me, titrate down while watching weight and appetite close. Find lower dose for maintenance, just use GLP for hunger control not further loss.
Third round of Amo R20, staying at 12mg for a while now with no problems. Split dosing every 4 days. Last two weeks brutal gastroparesis kicked in - sulfur burps, cramping, loose stools, way rougher than I had going up. Dropping a pound weekly for a year. Started 267, now 213. Sudden side flares after this long - anyone else seen that? Any ideas?
HGH doesn't wreck your natural production permanently. You get a temporary dip while running it but everything bounces back to where it was. Not like other stuff that shuts everything down completely. Never tested mine myself though, probably won't get a chance.
I felt it right away at the starter dose—nice surprise. Your body still needs food even when the appetite's gone. It's learning real hunger versus noise-hunger and eating smart when you think about it. That part's still work in progress for me, only 3 weeks in. Good luck.
GymGirl is doing the real work. 4-5 gym days plus 20k steps is not a casual commitment. The people who say the medication does all the heavy lifting clearly have not met anyone putting in that kind of effort alongside it.
The long-term safety picture on semaglutide is genuinely one of the more reassuring aspects - it's been used in clinical settings for a long time and the scale of real-world use by now is massive. That doesn't mean there are zero unknowns but the signal on serious long-term harms just hasn't materialized the way some people worried it might.
Two months on sema and slower results doesn't mean the medication is losing steam - some people just respond slower across the board. The assumption that everyone melts quickly is the comparison trap. Ups and downs then steady movement is the actual pattern for most.