It's called anhedonia, loss of enjoyment! Some people get it because GLP-1s act on the brain's reward pathways. I watched a video that explains a lot of the GLP-1 mechanism, and I sat through plenty of medical videos because I refuse to inject first and interrogate afterward lol. Understanding the mechanism comes first for me, before using anything. Personally, I barely want alcohol anymore, my boyfriend has no idea I'm on Semaglutide, though lately he gets on my nerves.