HDL Up, LDL Down? Share Your Tips!

Cardarine was created in 1992 by Ligand Pharmaceuticals and GlaxoSmithKline (GSK) as a metabolic agent for cancer, obesity, and cardiovascular disease. Phase 1 trials began in 2000 for hyperlipidemia, followed by phase I/II in 2002. The development of cardarine was stopped in 2007 due to safety concerns when preclinical toxicology showed it caused various cancers.
 
I heard a story of someone's dad eating a large bowel of oatmeal for a while before his blood test, and it significantly lowered his cholesterol, so his doctor wouldn't complain. There's science behind it too, as any box of Cheerios boasts!

My total cholesterol was 245, then statins got it down to 217. Tirz lowered it to 149. My LDL went from 159 to 136 with statins, and then 64 after tirz. I thought they must have mixed up my sample!

My HDL didn't change much: 63 at the start, 65 after statins, and 67 after tirz.
 
I researched this a while ago and made this plan for my partner. It lowered his LDL after a few months. It's not clinically proven, but it's based on academic studies.

For better Cholesterol Health:

A. Supplements

1. Omega 3 (2g)
* 1/2 T cod liver oil = 1.5g
* 2 Krill oil caps = 0.25g
* 2 Fish oil caps = 0.6g
* Total = 2.35g

*I prefer more krill and less fish oil, but he already had Costco fish oil at home.*

2. Flushing Niacin (2g)
3. Psyllium (2T/10g)

B. Nutrition

1. 6 servings of fish a week (salmon/sardine/mackerel)
2. 5 salads with 3 or more avocados each week
* *The salads were for convenience, fish, eggs, avo in one place for OMAD*
3. 12-18 eggs a week

C. Workouts (Weekly)

1. 2-5 hours Zone 2 cardio
2. 3-5 hours strength training

Update 1: Steel cut oatmeal might help, and you can add psyllium husk powder to it too.

Update 2: Berberine might help, but I'm not sure if it will have much impact if you're already on GLP-1s and have good insulin control?
 
I was using Chat GPT to try and get advice for myself, but remember to give it context about yourself:

* what types of foods you like and what kind of lifestyle you live
* and then tell it to imagine it's a highly trained and respected dietician, cardiologist, and men's health expert that is also an excellent chef

Then ask it your question... what types of meals would you recommend, or what advice would you have, for me to lower LDL, increase HDL, improve my lifestyle, and improve my health and energy?
 
Yep. Or it can misinterpret them. It can be a good start, but you have to ask it to give you the sources and then check to be sure that the source actually proves what it is saying.
 
I totally agree The-AF! My doctor wouldn't prescribe a statin even with LDL around 130, so I tried red yeast rice. It got my LDL down to around 70. Even then, she just said, "That's great!" I tried to explain that it wasn't regulated and I didn't know the content of active ingredients or anything, but she didn't care. I had to pay out of pocket for a CAC scan to prove to her that I needed treatment. I now take 10 mg ezetimibe, and my LDL is down to around 35! Ezetimibe is pretty cheap and good for folks who don't like statins or just can't take them. Found a new doctor, too, haha. All of this is part of living a healthier life (cardio 5x/week, much better diet, strength training 4x/week, etc.).
 
Glad you got on it and found a doctor who works with you. It sucks that they ignore important stuff like the fact that you're taking the same active ingredient as pharmaceuticals without knowing quantities or purity, etc.
 
I also did the exact same change! I'm shocked more people aren't on pitavastatin since it's the most metabolically friendly statin. My HbA1c went from about 4.9 to 5.3 on rosuvastatin, and I think it'll go back to normal...
 
Interesting results! I was reading on the other forum about GLP-1s and their impact on hormones, and studies actually show there can be a statistically significant increase in testosterone. Seems like GLP-1s might have benefits beyond just weight loss and blood sugar.
 
The-AF said:
Interesting results! I was reading on the other forum about GLP-1s and their impact on hormones, and studies actually show there can be a statistically significant increase in testosterone. Seems like GLP-1s might have benefits beyond just weight loss and blood sugar.
Click to expand...

That's interesting news!
 
Wow, I love seeing people taking control of their health! I saw a post from a 66-year-old woman who lost over 100 pounds and went from a BMI of 45.6 to 25.3. Her body fat went from 52.2% to 22.3%, and she added muscle mass! So inspirational!
 
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