Life changing! Down 6 stone!

Hong Kong Yanpep International
If only I could convince my mom. Fear's holding her back but this could transform her life. Dealt with hot flashes for fifteen years.
 
Exactly. Worth making a hashtag for. I keep quiet about mine mostly. Only share if someone really pushes and I think they're genuinely interested in changing.
 
That's really common after dropping 90 lbs. Body slows down and adapts at some point. Doesn't mean it stopped working, just a slower phase or plateau for a bit. A lot of people sit stuck for weeks or months before it moves. Usually small adjustments or just staying consistent. Keeping 90 lbs off is already a huge win.
 
from a pharmacology angle, that logic doesn't line up with how receptor regulation works. people usually take breaks to let receptors reset and skip the tolerance thing - sometimes eight weeks off, then restart at even a lower dose. otherwise you max out and stop responding.
 
switched from trulicity to mounjaro at 2.5, bumped up monthly — now on week 2 of 7.5 and miserable. 46f, 260 lbs. first week puked 13 hours after the shot, better by day 3. this week still nauseous, added diarrhea and my second period this month (heavier). forcing down crackers and ginger ale. new doc wants me ramping every month.
 
Six days on mt2 at low doses. A week later, moles on my face got way darker and really visible (nose especially). Healing acne scars darkened too. Didn't expect that. Stopped immediately. Anyone know if this fades or if it's permanent?
 
6mg to 8mg and loss happening quickly with the side effects manageable and then 4mg maintenance clean is the dose arc most people are hoping to hit. the OP's biggest loss at the higher dose is consistent with what you're describing. the side effects that go away when you drop to maintenance are almost always worth pushing through during the loss phase.
 
'Your experience will be uniquely yours' is such an important thing to say to someone starting out. The forum can skew toward the difficult cases and the complicated responses. The higher dose moving more weight is the typical pattern and not letting the outlier stories set your expectations is the right headspace to go in with.
 
My whole approach was just stick with whatever's working. Never needed to go past 10mg and I'm down 125 pounds so far. Sat at 5mg for around six months of that.
 
Went from 220 down to 132 without ever going past 5mg. Medication just clicked for me right from day one though. Some people need those higher amounts before they actually feel anything.
 
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