Long-term Mounjaro users - how many years in, and what is your maintenance dose?

Hong Kong Yanpep International
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amberhummer

Well-known member
Been reading through old threads for a while and had a question the long timers might answer. My own treatment ran about six months, I lost around twenty two kilos, and I came off the injection back in spring. Weight has stayed stable since without the medication, so purely out of curiosity, how long have the folks who consider this a lifelong medication actually been taking it continuously. Everyone compares it to glasses or blood pressure pills, take it forever and the effect stays the same, but from what I've personally experienced and from plenty of other threads, the appetite suppression seems to fade once you've sat at the same dose for a long stretch, even for people who never needed to go past a moderate dose to reach goal. So what does the maintenance dose look like for someone several years in, and does appetite control hold steady or has it dropped off. Mainly interested in hearing from the weight management side rather than the diabetes side.
 
Fair point. Thats said Ive also heard of people regaining even while sticking with mounjaro the whole time. Genuinely curious to hear from folks in maintenance on it for 5 to 10 years specifically. Not against making this a lasting part of the plan, but habits outside the medication will always carry the most weight in the end.
 
august 2022 is when mounjaro entered my routine, and i kept a running tally of weight and measurements lost the whole way through. left arm worked best as my go-to injection spot, with the left side of my stomach a close second.
 
Coming up on two years off now, quit January 2025, holding near 79-80 kilos but crept to about 82. The only periods i carried less weight were while playing a sport - rugby stuck longest, though a team sport gets rough once school ends. Getting older i noticed i was turning into a grumpy old man about food, it became a selfish habit. Always had a sharp comeback ready if my weight came up, which sat near 116 kilos then. Knew i needed to lose it, and i know my own personality enough to admit that without Mounjaro i never would've stuck with it long enough to see results. It reset things, same way nicotine patches made me forget to want a smoke, Mounjaro made me forget to want food. Switched to my grandparents old plates, smaller than modern ones. Diet stayed mostly the same, just tweaked
 
Forget mounjaro for a second. Your body right now isn't the body of someone who's always sat at a healthy weight - your metabolism wasn't working well, got treated, that treatment stopped, and you shed a huge amount of size, so you're in recovery mode, not just back to normal. While on it your system ran more efficiently, food gave less brain reward, digestion slowed, hunger got muted. Now you're eating like you're still on it without any of those advantages. All that's left are the tools people have always used: willpower, muscle, protein, staying active. Thinking you just need to not add weight back isn't enough, you're still in diet mode during maintenance. People have kept weight off long term before through plain dieting for decades.
 
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