Math check for Reta dose?

Fox

Fox

Well-known member
Hey all,

Just making absolutely sure I have this right before I start. I'm a bit nervous about messing up the dosage.

If I get a 5mg vial of Reta, I should mix it with 2ml of bac water, right? I do that by drawing the bac water and injecting it slowly into the Reta vial, letting it dissolve completely.

Then, each 0.1ml would equal 10 units on the syringe. So, for a 1mg dose, I'd draw 40 units, which I think is a good starting point?

Any advice is appreciated!
 
If you reconstitute a 5mg vial, then 1mg is just a fifth of whatever volume you ended up with.

Since 1mL = 100 units, then 0.4mL, or 40 units, is a fifth of 2mL. So yeah, that math seems right.
 
I swear by a reverse calculator. I even made my own (link below) and make sure you know the REAL mass tested and confirmed in your vial, and not just what's on the sticker.

Avoid doing math entirely if you can. It's no one's friend.
 
A 5mg vial has five 1mg doses. So, put in 50 units of bac water. Then 10 units is 1mg. Or, put in 100 units, and 20 units is 1mg. I like smaller amounts and less math, lol. But you were correct. Calculators are helpful.
 
Awesome that you're asking! It's always best to confirm. The math works out if the vial truly contains 5mg. Batches are often +5% overfilled, potentially giving you a 10% bonus. Good for the budget, but maybe not otherwise. Check the Certificate of Analysis from your supplier. Calculators are your friend. Personally, I'd use 1ml BAC and dose 20 units, but that's just me...
 
Smaller injection volume.

I favor larger volumes. Here's why:

1. A more diluted solution might reduce injection site reactions. Usually not a problem with GLP-1s but common with other stuff.

2. Larger volumes are easier to measure accurately. Some dose recommendations require tiny amounts. Good luck drawing up 8 units in a 1ml insulin syringe! For volumes under 30 units, I prefer a 0.5ml syringe.
 
A 5ml vial that *should* contain 5mg may really contain 5.5mg. 5.5 is 10% greater than 5, which could be significant. Always double-check my math and correct me if I'm wrong!
 
You mentioned earlier that a 5% overfill isn't unusual, which would mean 10% in this specific case.

Percentages are percentages. Maybe you meant a 0.5mg overfill, which would *be* 10%?

I don’t stress about overfills, or starting at a low percentage of typical dosing schedules.
 
If I start with a small 1mg weekly dose, does it really matter if there's a slight overfill, considering most people begin Reta at 2.5mg?
 
It depends on how you respond. Trial runs started at 2mg, but I began with 1 mg twice a week before going to 2mg, then progressing to 4 mg, 6 mg, 8 mg, and finally 10 mg, spending 4 weeks at each level. Some people stay at lower doses like 2 mg or even 1 mg due to side effects. If you respond well, it shouldn't be an issue.
 
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