Meds Update: Dosing, supply, and when to call the doc!

Izzy1994

Active member
Hey everyone!

Hope you all had a fantastic weekend. It's been a bit since our last reminder post, so I wanted to address some recent questions, mostly about dosages and getting your meds when there are shortages.

Remember, the half-life of Tirzepatide is about 5 days, meaning it takes roughly a month for it to clear your system. If you've been off it for a few weeks due to supply issues, the manufacturer suggests restarting the titration. This might not be necessary for everyone, but think about how you reacted to it before. If you had bad side effects, jumping back to a high dose could bring them back, maybe even worse.

Talk to your doctor about maybe lowering your dose *briefly* if you've been without your meds for a few weeks. I know no one wants to lose progress, but it beats dealing with nasty side effects that can really mess things up.

Honestly, I'm seeing too many posts about negative side effects after breaks in treatment. These meds are supposed to help you feel better, not worse.

And always, check with your doctor. They know best when it comes to dosing.

Now, about side effects:

While some stomach issues are common with Tirzepatide, extreme nausea with constant vomiting or diarrhea isn't. Diarrhea and vomiting can cause dehydration, electrolyte imbalances, fainting, and heart issues. Serious problems are rare, but they often happen when people ignore severe side effects.

We want to support each other, and sometimes that means telling someone to see their doctor. Especially if they say things like "I can't keep anything down," "I've been throwing up for days," or "I'm too weak to move."

Asking for advice when you're that sick isn't a good idea. You need a doctor.

Another common question: "I've only lost X pounds this week/month. Is that normal?"

Usually, the answer is "yes." *Normal* weight loss varies a lot. Search the forum for stories about different rates of weight loss. If you still have questions, give us details like your dose, other health issues, starting weight, and calorie intake.

People are using these meds for various reasons. These reasons can affect results. Don't get discouraged if the scale isn't moving as fast as you'd like. I had weeks with no loss, and even a couple of month-long stalls. But I reached my goal, and you probably will too! I wish I had magic words, but I don't. Just trust the process. Obesity is complicated enough, and adding metabolic issues like diabetes, insulin resistance, or PCOS makes it even more complicated.

Finally, to help with finding medication, we have a chat.

Some people didn't like being sent to the chat. We made it because *others* were tired of seeing shortage posts. You can't please everyone!

Weezie and I try our best to help. If we send you to your doctor, the availability chat, or the search bar, it's because we want you to get the best help possible. The mods and other members really want to help!

Have a great week!
 
You're awesome! I'm very grateful for this forum and for you two mods. I learned much when I started 6 months ago. This forum has meant so much to me. It's like having pals and resources in my pocket. It's comforting and very helpful. Thanks!
 
I saw someone celebrate their one-year anniversary on a GLP-1 and it was so inspiring. They mentioned facing supply issues and having to lower their dosage at times, which is super relatable right now. But they also talked about increasing exercise to manage stress and keep their weight loss going. That's such a great reminder that it's not just about the medication! They lost about 30% of their starting weight in a year! Incredible!
 
Someone else mentioned that they are insulin resistant and trying to lose about 50% of their weight. I wonder what their starting weight was? I am 160cm and started at 110kg. Now I'm down to 94kg since July!
 
Very slowly building supply. Gotta buy secretly or hubby thinks I'm crazy. Only just learned I'm getting powder overseas not domestic pharmacy. Doesn't understand pharmacies get from same place we do. Sema dropped price since late year so taking advantage.
 
I totally get it. My doctor was skeptical about mine too at first, but I told her I'd done my homework and this was the best choice for me. Honestly, I said she needed to think about why she became a doctor if she won't support patients who've done the research. I'm 60+ down now, almost zero fibro flakes, my migraines went from daily to super rare, and I'm easily hitting 25k steps. It takes time to find someone open-minded, but they don't have to take responsibility for your choice, just respect it.
 
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