MOTS-c AND SLU at the same time?

[Groovy_Bro]

Solid clumps from shipping usually recon fine - gentle rotation in warm water, not shaking, and it typically dissolves within a few minutes. Cloudiness after full dissolution is the real flag.

 

[SunnyJourneyLiving]

Running both at once is viable but makes it harder to isolate what's driving adaptation - if budget isn't the issue, the combination makes sense; if it is, MOTS-C first gets the mitochondrial baseline before adding the exercise mimetic.

 

[hummus-runner]

the AMPK-mTOR antagonism is the reason MOTS-c and compounds that work through mTOR activation make less sense to run simultaneously - the pathways are pulling in opposite directions. stacking MOTS-c with SLU-PP-332 is different because they hit separate mitochondrial targets, which is why the combined approach makes mechanistic sense when the goal is both metabolic flexibility and energy output