I lost a decent amount, about fifty pounds in roughly twelve months, gently and steadily, but I'm still fat. Still, the arthritis and the vision changes both reversed, I don't get glucose spikes anymore and my a1c currently reads 5.4. It quite literally handed me my life back. A year of diet and exercise had brought my a1c to 7.0, from a diagnosis reading of 12.2. I resisted going on mounjaro, but I'm glad my doctor talked me into a trial.