Optimal Reta Dose?

Hong Kong Yanpep International
Half-life of six days meaning blood levels need time to build is the explanation for why 3-4 weeks of inconsistent dosing can't give you a fair read. The OP at 1.5mg weekly with end-of-week hunger is the steady-dose patient version - and that end-of-week signal is the dose ceiling or dosing frequency question. How long have you been consistent at 1.5mg?
 
Been on reta for a few months now.
Currently down a solid chunk from where things started.
But recently moved up a dose level since the lower amount let me eat basically anything and still feel hungry.
Still running into that same issue at the current amount, wondering whether pushing even higher makes sense.
Also running low on remaining supply if the higher amount becomes the new normal.

Thanks
 
Keep in mind your doses are small, since the clinical trials began at 2mg, so you're still under where the trials started. Go up to 2mg and see from there. If you've reached 3 or even 4mg and still see nothing, that's the time to look at other options. What's your activity like too? With reta and no exercise, about 4 pounds seems plausible at such a low dose.
 
According to the studies on reta, youre probably already past the effective range. The benefit topped out near 8-9mpg. Youre likely hitting a different roadblock that reta cant address. Personally Id look elsewhere instead of raising the dose.
 
People say the smallest effective dose is best. I think the trials started at 2mg, but not sure about reta. Tirzepatide .5 seemed like a lot to me.
 
If reta gives you no side effects, you'd only add cagri if you're REALLY fighting appetite at around 8mg and don't want more reta. 1.5mg doesn't even count as a starter dose; expect 3-4 weeks before it suppresses appetite well, and once-weekly dosing may leave you starving by day 5, it does for me. Most people say glucagon activation doesn't kick in until 6-8mg.
 
Sensitivity to the medication varies hugely. 1.5mg of reta shut my appetite down completely, and thats a fairly small dose. The studies took participants as high as 12mg. I couldnt manage a normal meal for months on that.
 
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