Retatrutide storage: am I doing this right?

Cat_Life

Cat_Life

Well-known member
Hey everyone,

I'm in my second week using retatrutide and just got one vial to start. I'm kinda new to all this, so sorry if this is a silly question, but I'm trying to figure out the best way to store it. I'm planning on ordering a bigger supply soon, and I'm not sure how to handle the storage.

1. Should I mix all the vials at once and then just keep them in the fridge? They're 10mg vials, and I'm taking 4mg a week, so each vial would last about 2.5 weeks.
2. Or should I mix them one at a time as I need them and keep the unopened vials in a dark, cool place like a drawer?

I'm worried about them going bad. I've read that a mixed vial can be good for up to maybe 6 weeks in the fridge, but I don't know about the powder form before it's mixed.
 
I'd stash most of your unmixed vials in the freezer. People debate whether the defrosting freezers mess with things, so you could put them in a cooler bag with a cold pack just in case.

I'd mix maybe four vials at a time and keep them in the fridge for easy use. Most people figure they're good for around three months that way, assuming you use sterile water and good technique when mixing and measuring.

Or, what I plan to do from now on: mix the whole bunch, then freeze all but the one you're actively using; move that one to the fridge a day before you need it and keep it there until it's gone. A study showed freezing and thawing didn't hurt tirzepatide too much.
 
That freeze/thaw data is for tirzepatide... I thought reta might be a little more delicate? I'd be okay freezing tirz as long as the vial had room to expand so it didn't crack, but I haven't heard the same for reta yet. I'd probably just freeze the retatrutide powder as is.
 
I was talking to someone about doing a freeze/thaw test for reta, sema, and cagrilintide too. I'll probably suggest reta as a test subject when my current study progresses.
 
I don't believe that storing at very cold temperatures is necessary for short-term storage. I know a vendor selling Reta made in August-24 that's been at room temp the entire time, and it's still good.

Less than a year: room temp is fine.
1-3 years: fridge.
3-5 years: -20C freezer.
More than 5 years: -80C freezer.

There's a debate on whether home freezers are even better than fridges, though.

I keep most of my freeze-dried peptides in an insulated container in a -20C manual defrost freezer I got on Amazon.
 
So, piggybacking on this thread about reconstitution, is anyone familiar with GHRP2? I just got a 15mg vial with water from a compounding pharmacy.

I'm going to use 100mcg, four times a day, along with Sermorelin. Any tips on how much water to mix in for that dose? Thanks!
 
Hey @Heal_Strong, to make the math easy for your GHRP2, if you add 7.5mL of bac water to the 15mg vial, then each 1.0 mL will have 2000mcg, 0.5 mL will have 1000mcg, and 0.05mL will have 100mcg. That tiny dose would be 50 units on a regular 1mL syringe, which can be hard to measure. So, using a 0.5mL insulin syringe might be easier to draw such a tiny amount accurately!
 
Wow, lots of different opinions here! Thanks, everyone. I'm leaning towards freezing the powder until I need it, like @ShotHealth suggested. Seems like the safest bet. Maybe I'll just mix one or two vials at a time then.
 
Oh wow, thanks @Val_07! That makes perfect sense. The prescription is already on its way with insulin syringes and everything, so I guess I was just jumping the gun a bit!
 
Thanks for the input! I still have some weight to drop, roughly 20-30 pounds of fat remaining. Not just relying on the scale since I've restarted at the gym with resistance training. I just began on 0.25 of semaglutide and haven't noticed much hunger suppression yet. Did you feel anything right away? Did your dose go up?
 
theoretical question: if rfk actually softens the line on compounded peptides officially, could i use my hsa to shop around? me and my wife have decent savings. even at inflated prices, non-glps might cover a year or eighteen months, zero out of pocket.
 
Peptides are delicate—inject BAC slow down the side, no shaking. Recently grabbed hefty reconstituting needles and when I used one the vacuum sucked BAC in fast and it bubbled. Clear solution now, looks normal, but worried I damaged the peptides.
 
You don't have to filter into another vial but most people do it just to clean up particles and make sure it's sterile. First few vials I didn't bother but it's smarter to filter. Just means you need clean vials, filters, and a steady hand to not mess it up.
 
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