Sema making my OCD worse? Anyone else?

SlightlyLess88

SlightlyLess88

Well-known member
I think semaglutide is messing with my OCD. I started taking it a few days ago, as prescribed of course. I've had some stomach issues, which I expected, but my OCD feels like it's on overdrive, especially my relationship OCD. Nothing seems to help, and I'm feeling really blah. I have felt this before with other medications. Has anyone else had this experience with semaglutide or another similar med?

UPDATE: I stopped taking sema and started feeling better pretty quickly. Guess it wasn't the right med for me! My husband is still on it and has zero mental side effects, just less hunger. So weird.
 
I can relate to the lack of motivation! I just want to stay in bed all day. I wonder if the sema is causing that too?
 
Are you making sure you're eating enough? I have to be really careful about that, because that can trigger issues for me. Semaglutide makes it easy to forget to eat.
 
I have pretty severe OCD, and I haven't noticed my symptoms getting worse. But my OCD does make me hyper-aware and anxious about new medications and their potential side effects. I definitely found myself overthinking every possible side effect and wondering if I was experiencing it. OCD can get worse with stress or anxiety. It could be from taking something new or something else entirely. Good luck!
 
Last year when I was on a similar medication, I had the worst OCD flare-up of my life. I didn't even realize I had OCD before then, it was so mild. Now I'm on medication for it and my life has been turned upside down. I don't think doctors fully understand how this can affect brain chemistry. I didn't sleep for half a year and lost everything.
 
There's some evidence it affects serotonin levels, and it seems to affect some people more than others. It can reduce cravings for things like alcohol or smoking pot, and in some it seems to numb all desires. It can be good or bad for addictions, but too much of any one thing isn't great.
 
MyBro said:
I can relate to the lack of motivation! I just want to stay in bed all day. I wonder if the sema is causing that too?
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It could be! I know sometimes I feel kinda blah and just wanna chill instead of doing stuff.
 
Weight loss can bring up old feelings. I've struggled with my weight for years. I wonder if that contributes to it too.
 
CurvyToLurky said:
I have pretty bad OCD but it's been in "remission" since I started this medication, which is weird.
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That's interesting! Everyone responds so differently. Maybe it's related to how it impacts your gut biome?
 
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