Stacking sema/tirz - anyone tried it?

[MedRN]

I'm on MJ and thinking about adding Tesofensine. Anyone have experience with this combo? Did you take it orally or via injection? My doc is open to it and suggested it; I'm just doing some research.

I tried Teso. The appetite suppression was really minor and it messed with my sleep way too much.

 

[TrimSis]

Hmmm, sounds like I should be careful with the Teso then. I'm already a terrible sleeper. Thanks for sharing your experiences, everyone!

 

[Alex_33]

Been stacking sema and tirz each week. Was stuck at 15 on tirz alone. Fingers crossed this dose bump does the trick.

 

[Caffeine_Queen]

Did tirz! Tried stacking it with sema first and got so nauseous. Then attempted cagri but I think the dose was way too strong. I was basically down for 3 days straight.

 

[Curated_Cloud7]

Took sema for months without problems, then tried tirz once and got palpitations the next day. Couldn't switch back. Cardiologist says everything checks out but the palpitations won't stop. It's been rough.

 

[Gym_Done757]

Sema and tirz hitting both GLP-1 and GIP receptors is why the food noise coverage tends to exceed either alone.

 

[amberhummer]

My doctor threw out the idea of combining it with something else to shed those final pounds. Did some research on other combos too. Might be worth exploring what works for your situation.

 

[Rene_2001]

A handful of people here have tried it and shared results but there's no clinical framework for dual-GLP stacking. Most who do it go low dose on both and watch closely. No safety data either way - worth knowing what you're getting into.