I make a point of being upfront about both what I take for depression and my GLP1 use. Doing that helps fight off any lingering shame I'm tempted to bottle up, and it shows others they're not alone in this. Honestly picked up this coping approach from a childhood spent around parents skeptical of vaccines. Feels a little like a dare, if I'm being honest.
Only ever gotten curiosity back. I'd default to assuming good intentions if someone brings it up. 'Yeah, it's genuinely changed my life! Curious about it yourself? Considering trying a GLP1?' That's basically my go-to line. Hope you land on something that clicks for you too!