Switching off metformin?

[Peptide_Journey]

2mg for maintenance with A1C in normal range, kidneys still improving, and cardiovascular benefits continuing is the full metabolic picture that makes the stop question hard to answer. The OP's doctor suggesting switching from metformin to Ozempic makes sense mechanically - the GLP-1 mechanism hits cardiovascular and kidney benefit pathways that metformin doesn't cover. What's the main hesitation about making the switch?

 

[chickpea_recomp]

A1C from 9 to 5.6 in 25 months is the kind of movement that changes your long-term risk picture significantly. 11% body weight on T2D can have meaningful metabolic effects even when the loss feels slow. The T2D response profile is different from someone who doesn't have it - what does your doctor say about where things are headed from here?

 

[lanky-newbietoo8712]

Interesting! I ended up quitting metformin entirely, but really ramped up my daily fiber to manage the constipation instead.

 

[m6-later71]

On both actually. Doctor switched me from regular metformin over to the extended release version. Feeling great since.