Tessamorelin rebound?

[Veggie-Coffee]

I was looking at some research and it seemed like folks who stopped Tessamorelin tended to regain the visceral fat they'd lost. I'm guessing a lot of us here are using other weight management peptides like Retatrutide, GLP-1s, or Tirzepatide. Has anyone ever cycled Tessamorelin alongside something else and then stopped taking it? What happened?

 

[Mel_2006]

Weren't those studies on HIV patients dealing with fat issues from their meds? It'd make sense they'd gain it back if they kept taking the meds causing it. If you change your lifestyle and diet, the fat shouldn't come back. But just like with any weight loss, bad habits bring it back.

 

[NolaNana]

When I stop taking it, I drop a lot of water weight. I think Tesa fills my muscles with water, which makes my fat percentage look better on the scale. Then it jumps back up when I stop using it. Maybe it messes with the numbers, who knows! My body fat is good either way, but I just wonder.

 

[DropPath282]

That makes sense. Tesa can cause you to retain water. So when you stop, you lose water weight without losing actual fat. That means fat makes up a bigger part of your remaining weight, raising the percentage.

 

[tirzepatide-convert]

Visceral fat doesn't come back overnight. It takes weeks, or even months, depending on how poorly you eat, lol.

 

[JerseyGirl82]

Is visceral fat always on top of muscle?

 

[Ant_Story]

Good question, @JerseyGirl82. I looked it up.

Visceral fat isn't always above muscle; it's actually the opposite in the abdominal area. It's found deep inside your abdomen, around your organs, beneath your abdominal muscles. Subcutaneous fat is just under the skin and above the muscles -- the stuff you can pinch.

Visceral fat is deeper, hidden behind the muscles, which is why it's harder to target with exercises like crunches and more linked to health issues.

 

[JerseyGirl82]

Thanks, @Ant_Story! Since I've been on GLP-1s, I've lost all the pinchable fat in my stomach (used to inject there, but it got annoying), but it still sticks out a bit. Hoping Tesa will help.

 

[Veggie-Coffee]

Thanks everyone, lots of great info. I'm also curious if that fat comes back as quick as the water weight when you cycle off. Anyone have metrics on that from dexa scans or similar?

 

[Drop_Pal]

I can relate to the GLP-1 stomach 'sticking out' even after losing the pinchable fat. I'm hoping to get down another 10-15 pounds. It's not easy or a straight line. I lost about 55 pounds on Mounjaro so far and am now trying to maintain it.

 

[tirzepatide-convert]

I can relate to the GLP-1 stomach 'sticking out' even after losing the pinchable fat. I'm hoping to get down another 10-15 pounds. It's not easy or a straight line. I lost about 55 pounds on Mounjaro so far and am now trying to maintain it.

You look at least a decade younger! Congrats on your maintenance journey and the A1c!

 

[Veggie-Coffee]

That's awesome @Drop_Pal! Maintaining is a big goal, how long have you been off?

 

[Drop_Pal]

That's awesome @Drop_Pal! Maintaining is a big goal, how long have you been off?

I'm actually not completely off yet, just taking a break. I'm about a month into a 6-month treatment program for BED and want to see how my body responds without it. It's also been helpful for some of the shortages. I will probably go back on a lower dose after.

 

[Chris_2002]

those CJC allergic reactions scared me too. if it's just about keeping things humming, sermorelin does sound way safer to me than dealing with all that fallout.

 

[Scale_Jail_Inmate]

why not stack ss-31 and mots-c at the same time? been thinking about this for an endurance event coming up — any insights on the protocol?

 

[SilverLake]

Had a procedure a few months back and they didn't ask me to stop. Heard the same from others. Guess it's up to the anesthesiologist.