Tirz insomnia--is it what's added to it?

ShrinkAF

Well-known member
Hey everyone,

I know sleep problems with tirz are all over the place, but I wanted to try a more focused chat about possible reasons.

I've been using a compounded version, and it's messed with my sleep. What's odd is that different versions with slightly different ingredients seem to mess with me more. The first batch had B12 and glycine, the second had l carnitine -- which absolutely ruined my sleep.

I'm curious, for anyone having sleep issues, have you noticed if it happens more with compounded stuff with extra ingredients, questionable sources, or the name brand version?

I realize this is really specific, but I was curious what people thought.
 
I also had sleeping problems when I began Tirz. I experimented with both the name brand and less reputable sources. No difference.

For me, the issue was waking up super alert (almost energized) at 2 or 3 in the morning, then being unable to go back to sleep. I think that Tirz might lower blood sugar while you sleep. In some folks, that dip is big enough that your brain thinks it's a crisis. So, your body dumps 'wake up' hormones like cortisol and adrenaline to raise blood sugar. Those hormones are stimulants, so you wake up around 2–3 AM feeling wide awake.

To smooth out my blood sugar levels, I ate a small bowl of Greek yogurt before bed. Or you could try slow-release carbs like Extend bars. Both seemed to help. Though, honestly, swapping to Reta was the real solution. It didn't cause the 2 AM wake-ups and felt easier on my sleep overall than Tirz.
 
I've observed that insomnia only happens if I've had a bit of alcohol. Even half a beer is enough to mess me up. I know I'll wake up after like 2 hours of sleep and not be able to get back to dreamland.
 
Reasons for waking up between 2:00 and 3:00 a.m.:

Lots of people—especially older folks—wake up between 2:00 and 3:00 a.m. At this time, melatonin (the sleep hormone) goes down, and the brain can wake up easier. Also, blood sugar can drop.

Low blood sugar is a trigger that the body understands as stress, so it fires up the wakefulness system in the brain (orexin). This system is made to keep us awake. But as we age, it doesn't work as well at night. So even small things can wake us up.

New drugs like daridorexant address this issue. They reduce the wakefulness signal and help you sleep better without forcing sleep.

In short:
Waking up at 2–3 a.m. often is because of lower melatonin, blood sugar changes, and a wakefulness system in the brain.
 
I have that issue too, I can manage it. I'm also having trouble falling asleep, and sometimes sleep aids work, sometimes I need prescription antihistamines.

I've had insomnia before, so...

When I started, my doctor prescribed Ramelteon. It took a little bit to work, but it helped me get to sleep, which was a huge issue for me, maybe better than it had been in a while. But I'd still wake up at 3.

Now, with L-Carnitine, I can't sleep for like 5 days after. Only two months in, but still.

I didn't want to switch to Reta because Tirz was working -- and I just bought a bunch of it.... I'm stuck with it for a bit =P
 
used to be depressed, anxious, exhausted all the time. SSRI helped but felt hollow. now i sleep real and wake up rested. anxiety's gone. dropped around 22 lbs since january and hitting the gym 3x a week. feels like i got myself back.
 
that's a rough calorie deficit. even for a small woman 1400 is the floor. my guess is you're eating way too little & that's causing the hair loss. check a tdee calculator.
 
think it's the rapid loss doing it, not bad diet. bariatric folks deal with it all the time. read a lot of people say it's temporary tho.
 
the fatigue after a shot really messes with everything, right? sleep issues + body aches = no workouts happening. i'd def talk to your doc about dropping back to .25 so you can actually enjoy your days and get outside.
 
I'm 69 and turning 70 next month (still can't believe it). Year and a bit on this and I've dropped about 65 lbs—went from 24s to 12s. Game-changers for me: probiotics to keep digestion smooth, fiber/dried fruit to dodge constipation, magnesium glycinate for the insomnia, electrolytes when the tiredness hits, and a heating pad since I run cold even in summer.
 
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