Tirz/Sema mix - good idea?

I went up .5 at a time with the Tirz. If I jumped higher, I'd feel completely wiped out. The good news is the fatigue wore off after a few months, so I've been solid for about a year now. Methylated B12 helped me a ton with it.
 
Tirz and sema target different receptors - GIP for tirz, GLP-1 for both - so mixing is pharmacologically redundant and the dosing math gets messy.
 
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