Ugh, these side effects!

Just_Jilly_K

Just_Jilly_K

Active member
I was getting the worst tummy troubles from the medication, like awful gas that kept me up all night and then... well, you know. Tried simethicone but it wasn't cutting it. Then I remembered reading something here about an alternative similar to IBGard, and it's made a huge difference! So, a big thanks to everyone!
 
Aside from the meds mentioned, drinking about 2-3 liters of water a day and also taking probiotics for your gut should assist in keeping things flowing. Good luck!
 
Are you getting enough fiber in your diet? My doc said it's key to keeping things regular. I haven't had any issues so far, thankfully. I'm about to bump up to 7.5mg, and I'm a little worried that the side effects might kick in at the higher dose. Did the side effects hit you when you went up to 7.5mg, or was it a later increase?
 
Hey @D-Will-1964, the side effects started for me a little bit after I jumped to the 7.5mg dose. It wasn't immediate, but it definitely ramped up over a couple of weeks. Good luck!
 
It's worth noting that GLP-1 receptor agonists can significantly affect gastrointestinal function. A recent discussion with Dr. Camilleri from Mayo highlighted the importance of monitoring patients for GI side effects. Some studies suggest that changes in gastric emptying can occur. So it's good to be proactive with diet and supplements as many of you are doing.
 
For constipation, some of my patients have found relief with a small serving of raw fruit in the afternoon. Things like cantaloupe, pineapple, cherries, and strawberries can help.
 
I've heard others mention that chia seeds can be helpful for regularity too. I guess the high fiber content makes a difference. I might give that a try if the digestive enzymes stop working as well.
 
Thanks for the fruit tip @Reta_King363! I'll definitely try adding some of those to my diet. Maybe that'll help me avoid needing more meds!
 
Yes. Side effects might be tougher the next week but it's totally fine. Do this often when requesting refills late and pharmacy takes days.
 
Hang in there! It does get better. The first couple of weeks were the worst for me. Staying hydrated helped a lot.
 
The serious side effect list on MiraLAX is label language covering edge cases. For GLP-1 users doing occasional low doses for constipation, the actual risk is minor. The electrolyte concern is real only at chronic high doses or in people with kidney issues. Rectal bleeding means report it if it happens, not that it is expected. Starting low and using as needed rather than daily keeps the risk minimal.
 
The GI adaptation window is usually 4-6 weeks. Simethicone and peppermint oil both help with gas. Dose splitting is worth trying too.
 
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